The Citri Reticulatae Pericarpium (CRP), is the aged peel of Citrus fruit, which contains phenols, flavonoids, and polysaccharides. This study aims to investigate dietary CRP supplementation on the growth performance, serum biochemical indices, meat quality, intestinal morphology, microbiota, and metabolite of yellow-feathered broilers. A total of 240 yellow-feathered broilers (1.
View Article and Find Full Text PDFIt is well known that the function of granulosa cells (GCs) is closely related to follicular development, and and histone methylation have been implicated in follicular development. However, the specific mechanisms by which and histone methylation regulate follicular development are still largely unknown. To explore the specific mechanism of in regulating follicular development, in this study, we showed that the expression of in immature ovaries and small follicles was significantly higher than in mature ovaries and large follicles of sows, respectively.
View Article and Find Full Text PDFObjective: To investigate the correlation between uric acid (UA), urinary protein (UP) and umbilical artery blood flow related parameters and maternal and infant prognosis in patients with hypertensive disorder complicating pregnancy (HDP).
Methods: A total of 110 hDP patients who underwent prenatal examination and delivered in our hospital from June 2018 to May 2023 were selected as the HDP group. According to the prognosis of mother and infant, they were divided into normal prognosis group (n=80) and poor prognosis group (n=30).
Background: Obstructed labor (OL) and uterine rupture (UR) are common obstetric complications. This study explored the burden, risk factors, decomposition, and health inequalities associated with OL and UR to improve global maternal health.
Methods: This was a cross-sectional analysis study including data on OL and UR from the Global Burden of Diseases, and Risk Factors Study (GBD) 2019.
Objective: To explore the complications and pregnancy outcomes of vaginal dinoprostone vs. Cook's double balloon for the induction of labor among pregnancies complicated by small-for-gestational-age (SGA) at term.
Methods: This retrospective study included consecutive singleton pregnancies complicated by SGA treated at Fujian Maternity and Child Health Hospital between January 2017 and December 2021.
Hypertension is one of the most common chronic diseases in older people, and the prevalence is on the rise as the global population ages. Hypertension is closely associated with many adverse health outcomes, including cardiovascular disease, chronic kidney disease and mortality, which poses a substantial threat to global public health. Reasonable blood pressure (BP) management is very important for reducing the occurrence of adverse events.
View Article and Find Full Text PDFFatty liver, which is induced by abnormal lipid metabolism, is one of the most common causes of chronic liver disease globally and causes liver fibrosis. During this process, bone marrow-derived mesenchymal stromal cells (BMSCs) and hepatic stellate cells (HSCs) migrate toward the injured liver and participate in fibrogenesis by transdifferentiating into myofibroblasts. S100A8/A9 is a powerful inducer of cell migration and is involved in liver injury.
View Article and Find Full Text PDFCancer Immunol Immunother
July 2024
Background: Hypertension and frailty often coexist in older people. The present study aimed to evaluate the association of frailty status with overall survival in elderly hypertensive patients, using data from the Chinese Longitudinal Healthy Longevity Survey.
Methods: A total of 10,493 elderly hypertensive patients were included in the present study (median age 87.
The synergism of host Paris polyphylla medium, the monoculture, and the coculture led to seventeen new metabolites, including eight sesquiterpenes, 1-7 having uncommon structural motifs compared to similar caryophyllene derivatives, 8 with an unprecedented bicyclic framework, and three xyloketals (13-15) with unprecedented frameworks from Nigrospora lacticolonia; one polyketide, 17 with novel bicyclo [2.2.2] undecane skeleton, and five polyketide-terpenoid hybrids, 20 (one novel sulfated), 21-24 from Penicillium rubens.
View Article and Find Full Text PDFBiochim Biophys Acta Mol Basis Dis
June 2024
Procollagen-lysine 2-oxoglutarate 5-dioxygenase 2 (Plod2) is a key collagen lysyl hydroxylase mediating the formation of collagen fiber and stabilized collagen cross-links, and has been identified in several forms of fibrosis. However, the potential role and regulatory mechanism of Plod2 in liver fibrosis remain unclear yet. Mouse liver fibrosis models were induced by injecting carbon tetrachloride (CCl) intraperitoneally.
View Article and Find Full Text PDFFinite, atom-centered Slater basis sets are used to determine approximate Kohn-Sham molecular orbitals. This is achieved by minimizing the kinetic energy plus the sum-squared difference between the Kohn-Sham density and the full configuration interaction density. As a result of the finite basis, a weight factor is introduced to balance the two minimization components.
View Article and Find Full Text PDFTriple-negative breast cancer (TNBC) has attracted attention due to its poor prognosis and limited treatment options. The mechanisms underlying the association between circular RNAs (circRNAs) and the occurrence and development of TNBC remain unclear. CircZCCHC2 is observed to be upregulated in TNBC cells, tissues, and plasma exosomes.
View Article and Find Full Text PDFBMC Cardiovasc Disord
November 2023
Background: Albumin to fibrinogen ratio (AFR), a new inflammatory marker, has emerged as a useful indicator to predict adverse outcomes for several diseases. However, whether AFR could be a new useful indicator to predict mortality in HCM patients remains to be evaluated. The study explored the predictive value of AFR for HCM-related death in adult HCM patients.
View Article and Find Full Text PDFHealthy Kupffer cell (KC) pool is dominated by embryonic KCs (EmKCs), preserving liver homeostasis. How the KC pool varies upon injury remains unclear. Using chimeric mice with bone marrow (BM) cells labeled with enhanced green fluorescent protein, we identify that BM monocyte-derived KCs (MoKCs) become dominant in cholestatic- or toxic-injured livers via immunofluorescence and mass cytometry.
View Article and Find Full Text PDFFront Public Health
August 2023
Introduction: Mindfulness reflects attention to the present moment in a non-judgmental way and has been linked to individual autonomy and motivation, but conclusions are inconsistent. The purpose of this review was to summarize previous studies to explore the relationship between mindfulness and motivation and its intervention effects.
Methods: Literature searches were conducted in five electronic databases.
Following the publication of this article, a concerned reader drew to our attention that in Fig. 5C on p. 1704, showing histological images of mouse livers stained with H&E, unexpected areas of similarity were identified in terms of the staining patterns revealed within the data panels themselves.
View Article and Find Full Text PDF15-deoxy-Δ-prostaglandin J (15d-PGJ) exhibited potential to alleviate liver inflammation in chronic injury but was less studied in acute injury. Acute liver injury was associated with elevated macrophage migration inhibitory factor (MIF) levels in damaged hepatocytes. This study aimed to investigate the regulatory mechanism of hepatocyte-derived MIF by 15d-PGJ and its subsequent impact on acute liver injury.
View Article and Find Full Text PDFIntroduction: This study aims to explore the mortality risk in older people who drank alcohol in the past by varying the duration of alcohol abstention.
Methods: In total, 31,999 participants aged ≥65 years from the Chinese Longitudinal Healthy Longevity Survey (Waves 1998, 2000, 2002, 2005, 2008, 2011, 2014) were included. Duration of alcohol abstention was assessed by designed questions, and the study outcome was all-cause mortality.
Biochim Biophys Acta Mol Basis Dis
August 2023
Objective: A new inflammatory marker, namely monocyte-to-high-density lipoprotein cholesterol ratio (MHR), has emerged as a useful indicator for adverse outcomes in several cardiovascular diseases; however, the relationship between MHR and the prognosis of hypertrophic cardiomyopathy (HCM) remains to be evaluated. We examined the relationship between MHR and all-cause mortality (ACM) in Chinese adult patients with HCM.
Methods: We retrospectively performed clinical evaluation in 305 patients with HCM (median age: 52.