The association between radiotherapy and the prognosis of follicular lymphoma patients with different characteristics in the rituximab era: a cohort study based on Surveillance, Epidemiology and End Results.

This retrospective cohort study examined the association between radiotherapy and prognosis in follicular lymphoma (FL) patients, with stratification by age, Ann Arbor stage, primary tumor site, surgical status, and grade. Using data from the SEER database, we employed Cox proportional hazards and competing risk models to assess the impact of radiotherapy on overall survival (OS) and cancer-specific survival (CSS) in 7,551 FL patients. The association between radiotherapy and second primary cancer (SPC) was explored using Logistic regression model.

The protective effect of two highly branched polysaccharides from corn silk fermented by Lactobacillus plantarum against acute liver injury.

To valorize the natural resource of corn silk as hepatoprotective food supplement, two fractions of polysaccharides (F-CSP-W/S) have been separated and purified from corn silk fermented by Lactobacillus plantarum. F-CSP-W was mainly composed of Glc, Gal, Ara, Xyl, Man (66.62: 11.

Effect of pharmacogenomic testing on the clinical treatment of patients with depressive disorder: A randomized clinical trial.

Background: Pharmacotherapy is one of the primary treatment modalities for depression. However, there is considerable variability in the individual response to antidepressant medications. Personalized medicine guided by pharmacogenomic testing may hold promise in addressing this issue.

Bioinformatics analysis of high frequency mutations in myelodysplastic syndrome-related patients.

Background: Myelodysplastic syndrome (MDS) is a group of hematological malignancies that may progress to acute myeloid leukemia (AML). Bioinformatics-based analysis of high-frequency mutation genes in MDS-related patients is still relatively rare, so we conducted our research to explore whether high-frequency mutation genes in MDS-related patients can play a reference role in clinical guidance and prognosis.

Methods: Next generation sequencing (NGS) technology was used to detect 32 mutations in 64 MDS-related patients.

Adsorption of Cr(VI) from aqueous solution by a litchi shell-based adsorbent.

Cr(VI) is a toxic metal pollutant existing in industrial effluents. In this study, FeO and layered double hydroxide (LDH) were inserted into the litchi shell (LS) successively by the co-precipitation method to synthesize the modified magnetic litchi shell adsorbent (MMLS) for removing Cr(VI). The advantageous structure characteristics of MMLS were confirmed by XRD, FT-IR, SEM and the hysteresis loop characterization.

Up-regulation of CKAP2L expression promotes lung adenocarcinoma invasion and is associated with poor prognosis.

Aim: The purpose of this study is to consider the function of cytoskeleton-associated protein 2-like (CKAP2L) in lung adenocarcinoma (LAD) development and its prognostic value.

Methods: The mRNA expression of CKAP2L and its correlation with clinical factors in LAD patients were analyzed from the data taken from The Cancer Genome Atlas and The First Affiliated Hospital of Kunming Medical University. We constructed H460 and A549 cell lines with silenced CKAP2L using RNA interference.

TRIM22 knockdown suppresses chronic myeloid leukemia via inhibiting PI3K/Akt/mTOR signaling pathway.

Tripartite motif-containing 22 (TRIM22) is reported to participate in numerous cellular activities. Recent studies confirm that TRIM22 is a target gene for P53, and inhibits clonogenic growth of leukemic U-937 cells. The current study aims to discover the effect of TRIM22 in progression of human chronic myeloid leukemia (CML) and explore the related mechanism.

An Experimental Study on Micro Clinching of Metal Foils with Cutting by Laser Shock Forming.

This paper describes a novel technique for joining similar and dissimilar metal foils, namely micro clinching with cutting by laser shock forming. A series of experiments were conducted to study the deformation behavior of single layer material, during which many important process parameters were determined. The process window of the 1060 pure aluminum foils and annealed copper foils produced by micro clinching with cutting was analyzed.

Fabrication of Dish-Shaped Micro Parts by Laser Indirect Shocking Compound Process.

Compound process technology has been investigated for many years on a macro scale, but only a few studies can be found on a micro scale due to the difficulties in tool manufacturing, parts transporting and punch-die alignment. In this paper, a novel technology of combining the laser shock wave and soft punch was introduced to fabricate the dish-shaped micro-parts on copper to solve these difficulties. This compound process includes deep drawing, punching and blanking and these processes can be completed almost at the same time because the duration time of laser is quite short, so the precision of the micro-parts can be ensured.