Publications by authors named "Liyang Zou"
Article Synopsis
- Hypobaric hypoxia leads to high-altitude pulmonary hypertension, which can cause chronic mountain sickness (CMS) characterized by increased hematocrit levels.
- The study examined how arginine (ARG) affects CMS symptoms in rats exposed to hypobaric conditions, revealing that ARG improved body weight, appetite, and lung function while reducing harmful blood parameters.
- The research also found that miR-144-5p plays a significant role in mitigating the effects of hypoxia, as its reduction worsened anemia and lung damage, while ARG treatment upregulated miR-144-5p and decreased erythropoietin (EPO) signaling.
Objective: MicroRNAs (miRNAs) are essential biomarkers during development of human diseases. We aimed to explore the role of hypoxia-induced bone marrow mesenchymal stem cells (BMSCs)-derived exosomal miR-98-5p in myocardial ischemia-reperfusion injury (MI/RI).
Methods: BMSCs were isolated, cultured, stimulated by hypoxia and transfected with adenovirus expressing miR-98-5p.
Background: Neuromyelitis optica spectrum disorders (NMOSD) are associated with recurrent episodes of optic neuritis and transverse myelitis, often resulting in high attack-related disability. Therapeutic apheresis has been recommended as a second-line treatment for steroid-refractory NMOSD. To assess the efficacy and safety of two apheresis techniques, lymphoplasmapheresis (LPE) and therapeutic plasma exchange (TPE), in refractory NMOSD and to provide a new treatment option for patients with refractory NMOSD.
View Article and Find Full Text PDF[A Predictive Model for Hemoglobin Change before and after Collection of Apheresis Autologous Red Blood Cells in Patients].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
October 2020
Objective: To analyze the affecting factors of hemoglobin changes in apheresis red blood cells (RBCs), and to establish a predictive model for the evaluation of apheresis.
Methods: The clinical data of 130 patients undergoing selective surgery for apheresis autologous RBCs from January 2017 to December 2018 were collected. The change of hemoglobin and its affecting factors before and after apheresis were analyzed.
Somatostatin (SST) exhibits a wide range of physiological functions, including the regulation of tumor cell growth. Octreotide (OCT) is a synthetic analogue of SST that can be used to slow gastrointestinal bleeding, inhibit the release of growth hormone and impede gastrointestinal tumor growth. The aim of the present study was to investigate the molecular mechanism of OCT underlying the inhibition of gastric cancer cell proliferation.
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