SIRT6 mitigates oxidative stress and RSL3-induced ferroptosis in HTR-8/SVneo cells.

Dysregulation in placental trophoblast cells frequently results in oxidative stress, culminating in pregnancy-related complications. While iron is essential for fetal development, cellular ferroptosis due to elevated iron levels might mediate the emergence of preeclampsia (PE), presenting significant risks during gestation. We found abnormally activated oxidative stress and increased iron concentration in the placental tissues of PE patients.

Bao Yuan decoction alleviates fatigue by restraining inflammation and oxidative stress via the AMPK/CRY2/PER1 signaling pathway.

Ethnopharmacological Relevance: Baoyuan Decoction (BYD) was initially recorded in the classic of "Bo Ai Xin Jian" in the Ming dynasty. It is traditionally used for treating weakness and cowardice, and deficiency of vital energy. In researches related to anti-fatigue effects, the reciprocal regulation of AMPK and circadian clocks likely plays an important role in anti-fatigue mechanism, while it has not yet been revealed.

Interlayer coupling controlled electronic and magnetic properties of two-dimensional VOCl/PtTe van der Waals heterostructure.

The coupling of hetero monolayers into van der Waals (vdW) heterostructures has become an effective way to obtain tunable physical and chemical properties of two dimensional (2D) materials. In this work, based on first principles calculations, we systematically explore the electronic and magnetic properties of a 2D VOCl/PtTe heterostructure. Our results indicate that the ground state of the VOCl/PtTe heterostructure is a ferromagnetic (FM) metal with large magnetic anisotropy energy, among which, the VOCl "sublayer" shows FM half metallic properties while the PtTe "sublayer" shows nonmagnetic metallic properties.

Ab Initio Study of Structural, Electronic and Magnetic Properties of TM&(B@C) (TM = V, Cr) Sandwich Clusters and Infinite Molecular Wires.

The geometrical structure, electronic and magnetic properties of B-endoped C (B@C) ligand sandwich clusters, TM&(B@C) (TM = V, Cr), and their one-dimensional (1D) infinite molecular wires, [TM&(B@C)], have been systematically studied using first-principles calculations. The calculations showed that the TM atoms can bond strongly to the pentagonal (η-coordinated) or hexagonal rings (η-coordinated) of the endoped C ligands, with binding energies ranging from 1.90 to 3.

Flavor Components Comparison between the Neck Meat of Donkey, Swine, Bovine, and Sheep.

Donkey in China is well known for its draft purpose and transportation; however, donkey meat has attracted more and more consumers in recent years, yet it lacks sufficient information on its flavor components compared to other main meats. Therefore, in this study, volatile flavor compounds in neck meat of donkey, swine, bovine, and sheep were classified by electronic nose, then confirmed and quantified by gas chromatography-mass spectrometry. High-performance liquid chromatography (HPLC) and gas chromatography were used to quantify free fatty acid, amino acid, and flavor nucleotide.

Mean platelet volume predicts survival in patients with hepatocellular carcinoma and type 2 diabetes.

Background: Patients with hepatocellular carcinoma (HCC) having pre-existing type 2 diabetes (T2DM) have a poorer prognosis than those without T2DM. Moreover, accumulating evidence reveals that activated platelets play a crucial role in tumor and T2DM. The mean platelet volume (MPV) indicates platelet activation and is altered in malignancies.

Chemical constituents and bioactivities of Panax ginseng (C. A. Mey.).

Ginseng, Panax ginseng (C. A. Mey.

Study on Chinese medicine syndrome of colorectal carcinoma in perioperative period.

Objective: To explore the distribution characteristics of Chinese medicine (CM) syndromes and the rule of dynamic evolvement in patients with colorectal cancer at the perioperative period by applying a mathematical statistics methodology.

Methods: By using the overall sample date, and cross-sectional descriptive and prospective researching methods, the clinical data of CM symptoms of patients with colorectal cancer from the first day of preoperative care to the third, seventh, and tenth days after the operation were collected. The distribution characteristics of CM syndromes and dynamic evolution were concluded upon by experts, and then by building up a database through the use of EpiData3.