Publications by authors named "Liya Hou"
Article Synopsis
- The emergence of CRISPR-Cas systems has led to the development of efficient gene editing tools, but traditional methods for discovering these systems often overlook important variants due to their reliance on sequence similarity.* -
- A new AI framework called CHOOSER has been introduced to discover CRISPR-Cas systems without needing extensive training data, significantly enhancing the discovery process by utilizing protein large language models.* -
- Using CHOOSER, researchers identified 11 new Casλ homologs, doubling the known catalog, and experimentally validated one homolog, EphcCasλ, for its capability in self-processing pre-crRNA and potential in CRISPR-based pathogen detection.*
L. is a natural medicinal plant that has been widely used for its various pharmacological effects such as antidiarrheal, anti-inflammatory, and wound healing. This study aims to explore the antidiarrheal active ingredients of L.
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