Publications by authors named "Lixuan Tao"
Background: GeneXpert MTB/RIF (Xpert) assay was applied widely to detect Mycobacterium tuberculosis (MTB) and rifampicin resistance.
Methods: Retrospectively investigated the association among treatment histories, phenotypic drug susceptibility testing (pDST) results, and clinical outcomes of patients infected with probe A absent mutation isolate confirmed by Xpert.
Results: 63 patients with only probe A absent mutation and 40 with additional pDST results were analyzed.
Objective: A retrospective cohort study was carried out to research the effect of stent combined with laparoscopy combined with enhanced recovery after surgery (ERAS) in the operation of acute intestinal obstruction and to explore and analyze the prognostic factors.
Methods: During February 2019 to April 2021, sixty patients with acute intestinal obstruction cured in our hospital were enrolled. Randomly assigned control group patients ( = 50) were divided into the research group and control group patients.
High-dose gatifloxacin-based shorter treatment regimens for MDR/RR-TB.
Int J Infect Dis
February 2022
Article Synopsis
- A prospective observational study was conducted on MDR/RR-TB patients treated with a high-dose gatifloxacin-based shorter treatment regimen (STR) over 9 to 12 months, monitoring for adverse drug reactions (ADRs).
- Out of 42 patients, 35 successfully completed the treatment, while 6 failed due to ADRs, predominantly drug-induced liver damage and QT interval prolongation.
- The study highlighted the STR's effectiveness, but underscored the need to monitor and manage severe ADRs like hepatotoxicity and prolonged QT intervals during treatment.
Treatment of chronic tuberculous empyema by intrapleural injection of anhydrous ethanol.
Respir Med Case Rep
November 2018
Background: Anhydrous ethanol, for its part, has been successfully used to treat renal cyst, hepatocellular carcinoma and ovarian chocolate cyst et al. However, in spite of the high frequency of tuberculous purulent pleural effusion, we found that only a few very early studies that attempted to assess the use of intrapleural anhydrous ethanol in tuberculous effusions with signs of empyema. We report a patient who was injected anhydrous ethanol into pleural cavity to treat chronic tuberculous empyema.
View Article and Find Full Text PDF[Effect of oxidative damage on expression of myocardin and NF-E2-related factor 2 in myocardial cells].
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi
August 2017
With the oxidative damage model established in rat myocardial cells by hydrogen peroxide (H O ), the expression of myocardin and nuclear factor erythroid 2-related factor 2 (Nrf2) during oxidative damage and effect of myocardin on Nrf2 were preliminarily explored. The expression of the target gene was increased or decreased by transfection of plasmid DNA or shRNA, respectively. Cell proliferation was detected by sulforhodamine B (SRB) assay.
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