Development and characterization of gelatin peptides and peptide‑calcium chelates from tuna processing by-products of skins and bones.

This study used hydrothermal extraction to obtain gelatin from tuna processing by-products. After treatment, the yield (w/w dry weight) of gelatin from skins and bones were 70.22 ± 2.

Unlocking anaerobic digestion potential via extracellular electron transfer by exogenous materials: Current status and perspectives.

The efficiency of energy transfer among microorganisms presents a substantial hurdle for the widespread implementation of anaerobic digestion techniques. Nonetheless, recent studies have demonstrated that enhancing the extracellular electron transfer (EET) can markedly enhance this efficiency. This review highlights recent advancements in EET for anaerobic digestion and examines the contribution of external additives to fostering enhanced efficiency within this context.

Enhancing degradation of antibiotic-combined pollutants by a hybrid system containing advanced oxidation and microbial treatment, a review.

Antibiotics often co-exist with other pollutants, posing a significant threat to ecosystems. This review first examines the applications and limitations of microbial treatments for various types of antibiotic-combined pollutants. Then, it explores the mechanisms and application of hybrid systems that integrate advanced oxidation with microbial treatment, categorized into two-stage and intimately hybrid systems.

Magnetic Micromotors with Spiky Gold Nanoshells as SERS Sensors for Thiram and Bacteria Detection.

Surface-enhanced Raman scattering (SERS) is widely used in all kinds of detection due to its ultrahigh sensitivity and selectivity. Micromotors, when used as SERS sensors, or the so-called "hotspots on the fly", can combine both controlled mobility and SERS sensing capacity, and are ideal for versatile in situ detection. In this work, mobile SERS sensors are successfully fabricated by growing gold nanospikes onto magnetic microsphere surfaces.

Loss-Assisted Anomalous Hong-Ou-Mandel Interference Based on Nonunitary Multilayer Graphene.

Hong-Ou-Mandel interference is an intrinsic quantum phenomenon that goes beyond the possibilities of classical physics, and enables numerous applications in quantum information science. While the photon-photon interaction is fundamentally limited to the bosonic nature of photons and the restricted phase responses from commonly used unitary optical elements, we present that a nonunitary material provides an alternative degree of freedom to control the two-photon quantum interference, even revealing anomalous quantum interference paths that do not exist in a unitary configuration. An elaborate lossy multilayer graphene that can work as a nonunitary beam splitter is used to explore its tunability over the effective photon-photon interaction in spatial modes, and to verify the particle exchange statistics by its experimental implementation in quantum state filter.

Bivalent affinity binding-inspired PPARγ immobilization with selective conformation and improved ligand-binding activity.

Functional protein immobilization forms the basis for bio-detections. A series of one-point, site-specific immobilization methods have been developed, however, it still remains as a challenge how to avoid the proteins to move in all directions as well as conveniently regenerate the bio-devices. Herein, we have developed a bivalent affinity binding-inspired method for PPARγ immobilization using DNA aptamer and nickel-nitrilotriacetic acid (Ni-NTA) chelation.

Nontrivial evolution and geometric phase for an orbital angular momentum qutrit.

Photonic orbital angular momentum (OAM) offers a promising platform for high-dimensional quantum information processing. While geometric phase (GP) is the crucial tool in enabling intrinsically fault-tolerant quantum computation, the measurement of GP using linear optics remains relatively unexplored in the OAM state space. Here, we propose an experimental scheme to detect GP shifts resulting from the cyclic evolution of OAM qutrit states.

Sorting infrared optical vortices with a nonlinear angular lens.

Analogous to the regular lens, which spatially maps plane waves in the space domain to distinct points in the Fourier domain, the angular lens establishes the mapping relations between an angular mode and angular position, thus providing an effective toolkit for detecting an optical vortex. However, using the angular lens to sort infrared optical vortex modes via nonlinear optical processes remains relatively unexplored. Here, we design a nonlinear optical version of the angular lens to map the various infrared optical vortex modes to different angular positions in the visible region.

DNMT1 regulates human erythropoiesis by modulating cell cycle and endoplasmic reticulum stress in a stage-specific manner.

The dynamic balance of DNA methylation and demethylation is required for erythropoiesis. Our previous transcriptomic analyses revealed that DNA methyltransferase 1 (DNMT1) is abundantly expressed in erythroid cells at all developmental stages. However, the role and molecular mechanisms of DNMT1 in human erythropoiesis remain unknown.

Geometric interpretation and experimental test of Leggett inequalities with nonmaximally entangled states.

Leggett inequality states that nonlocal hidden-variable models might still be incompatible with the predictions of quantum physics. However, its theoretical and experimental demonstration is only in the scenario of 2-dimensional maximally entangled systems. An open question remains as to whether the Leggett inequality can be violated by nonmaximally entangled states.

Coherent categorical information triggers integration-related alpha dynamics.

To create coherent visual experiences, the brain spatially integrates the complex and dynamic information it receives from the environment. We previously demonstrated that feedback-related alpha activity carries stimulus-specific information when two spatially and temporally coherent naturalistic inputs can be integrated into a unified percept. In this study, we sought to determine whether such integration-related alpha dynamics are triggered by categorical coherence in visual inputs.

A Comparative Study on the Degradation Behaviors of Ferroelectric Gate GaN HEMT with PZT and PZT/AlO Gate Stacks.

In this paper, the degradation behaviors of the ferroelectric gate Gallium nitride (GaN) high electron mobility transistor (HEMT) under positive gate bias stress are discussed. Devices with a gate dielectric that consists of pure Pb(Zr,Ti)O (PZT) and a composite PZT/AlO bilayer are studied. Two different mechanisms, charge trapping and generation of traps, both contribute to the degradation.

Genetic mutation of Tas2r104/Tas2r105/Tas2r114 cluster leads to a loss of taste perception to denatonium benzoate and cucurbitacin B.

Background: Bitter taste receptors (Tas2rs) are generally considered to sense various bitter compounds to escape the intake of toxic substances. Bitter taste receptors have been found to widely express in extraoral tissues and have important physiological functions outside the gustatory system in vivo.

Methods: To investigate the physiological functions of the bitter taste receptor cluster Tas2r106/Tas2r104/Tas2r105/Tas2r114 in lingual and extraoral tissues, multiple Tas2rs mutant mice and Gnat3 were produced using CRISPR/Cas9 gene-editing technique.

Remote transport of high-dimensional orbital angular momentum states and ghost images via spatial-mode-engineered frequency conversion.

The efficient transport and engineering of photonic orbital angular momentum (OAM) lie at the heart of various related classical and quantum applications. Here, by leveraging the spatial-mode-engineered frequency conversion, we realize the remote transport of high-dimensional orbital angular momentum (OAM) states between two distant parties without direct transmission of information carriers. We exploit perfect vortices for preparing high-dimensional yet maximal O AM entanglement.

The role and mechanisms of PD-L1 in immune evasion during Talaromyces marneffei infection.

Talaromycosis, caused by Talaromyces marneffei (T. marneffei), is a systemic fungal disease that involves dissemination throughout the body. The ability of T.

Dual role of birnessite on the modulation of acid production and reinforcement of interspecific electron transfer in anaerobic digestion.

Achieving efficient anaerobic digestion of highly loaded substrates is one of the most challenging problems in the field of waste resourcing. Here, the addition of birnessite (2.0 g/L) to kitchen wastewater increased the acetate and final methane yields by 40.

Talaromyces marneffei suppresses macrophage inflammation by regulating host alternative splicing.

Talaromyces marneffei (T. marneffei) immune escape is essential in the pathogenesis of talaromycosis. It is currently known that T.

Construction of a murine model of latent infection and reactivation induced by Talaromyces marneffei.

Objective: To establish a murine model of Talaromyces marneffei (T. marneffei) latent infection and reactivation, providing a foundation for exploring the molecular mechanisms underlying disease relapse.

Methods: BALB/c mice were tail vein injected with T.

Colloidal tubular microrobots for cargo transport and compression.

Microrobot swarms have seen increased interest in recent years due to their potentials for in vivo delivery and imaging with cooperative propulsion modes and enhanced imaging signals. Yet most swarms developed so far are limited to dense particle aggregates, far simpler than complicated three-dimensional assemblies of anisotropic particles. Here, we show via assembly path design that complex hollow tubular structures can be assembled from simple isotropic colloidal spheres and those complicated, metastable, microtubes can be formed from simple, energetically favorable colloidal membranes.

Comprehensive Characterization and Global Transcriptome Analysis of Human Fetal Liver Terminal Erythropoiesis.

The fetal liver (FL) is the key erythropoietic organ during fetal development, but knowledge on human FL erythropoiesis is very limited. In this study, we sorted primary erythroblasts from FL cells and performed RNA sequencing (RNA-seq) analyses. We found that temporal gene expression patterns reflected changes in function during primary human FL terminal erythropoiesis.