Individualized vaginal applicator for stage IIb primary vaginal adenocarcinoma: A case report.

Background: Primary vaginal cancer is rare and most vaginal tumors are metastatic, often arising from adjacent gynecologic structures. Primary vaginal cancers are also more common among postmenopausal women and most of these are squamous cell carcinomas, with adenocarcinomas being relatively rare. Vaginal bleeding is the most common clinical manifestation of vaginal adenocarcinoma.

Comparison of sulfide-induced transformation of biodegradable and conventional microplastics: Mechanism and environmental fate.

Biodegradable plastics have been massively produced and used as potential substitutes for conventional plastics, resulting in their inevitable entry into the environment and generation of biodegradable microplastics (MPs). The sulfidation transformation of MPs is an important process for their transformation in anoxic environments (e.g.

Formation of extracellular polymeric substances corona on TiO nanoparticles: Roles of crystalline phase and exposed facets.

Nanoparticles (NPs) in the environment can interact with macromolecules in the surrounding environment to form eco-corona on their surfaces, which in turn affects the environmental fate and toxicity of nanoparticles. Wastewater treatment plants containing large amounts of microbial extracellular polymeric substances (EPS) are an important source of NPs into the environment, where the formation of EPS coronas on NPs is critical. However, it remains unclear how the crystalline phase and exposed facets, which are intrinsic properties of NPs, affect the formation of EPS coronas on NPs.

Effects of photochlorination on the physicochemical transformation of polystyrene nanoplastics: Mechanism and environmental fate.

With the increasingly severe plastic pollution, the environmental behavior and effects of nanoplastics (NPs) have attracted much attention. The transformation of NPs in natural and engineered environments (e.g.

ZEB1 interferes with human periodontal ligament stem cell proliferation and differentiation.

Background: Periodontitis can eventually contribute to tooth loss. Zinc finger E-box binding homeobox 1 (ZEB1) is identified as overexpressed in the gingival tissue of mice with periodontitis. This study is designed to decipher the mechanism of ZEB1's involvement in periodontitis.

Maxillary anterior segmental distraction osteogenesis to correct maxillary hypoplasia and dental crowding in cleft palate patients: a preliminary study.

Background: The aim of this study was to present comprehensive skeletal, dental and facial aesthetic outcomes and long-term stability of maxillary anterior segmental distraction osteogenesis (MASDO) for the treatment of maxillary hypoplasia in CLP.

Materials And Methods: Six patients with maxillary hypoplasia treated with MASDO by a miniscrew assisted intraoral tooth-borne distractor were included. Cephalometric radiographs were obtained before distraction (T1), after the consolidation period (T2) and after orthodontic treatment or before orthognathic surgery (T3).

An Immune-Related Gene Signature for Predicting Neoadjuvant Chemoradiotherapy Efficacy in Rectal Carcinoma.

Background: Locally advanced rectal cancers (LARC) show a highly variable response to neoadjuvant chemoradiotherapy (nCRT), and the impact of the tumor immune response in this process is poorly understood. This study aimed to characterize the immune-related gene expression profiles (GEP), pathways, and cell types associated with response or resistance to neoadjuvant chemoradiotherapy.

Methods: The transcriptomic and clinical data of Rectal carcinoma from the Gene Expression Omnibus database and Immune-related genes (IRGs) from ImmPort were downloaded to identify the differentially expressed immune-related genes (DEIRGs) between responder and non-responder to neoadjuvant chemoradiotherapy.

Evaluation of the position and morphology of tongue and hyoid bone in skeletal Class II malocclusion based on cone beam computed tomography.

Background: The aim of the study was to analyze the morphology and position of the tongue and hyoid bone in skeletal Class II patients with different vertical growth patterns by cone beam computed tomography in comparison to skeletal Class I patients.

Methods: Ninety subjects with malocclusion were divided into skeletal Class II and Class I groups by ANB angles. Based on different vertical growth patterns, subjects in each group were divided into 3 subgroups: high-angle group (MP-FH ≥ 32.

Comparative study of three composite materials in bonding attachments for clear aligners.

Objective: The aim of this study was to assess the operation time, shear bond strength, placement accuracy and wear resistance of 3 composite materials (Filtek Z350XT, Filtek Z350XT Flowable and SonicFill) that were used to make attachments for clear aligners.

Settings And Sample Population: Laboratory of Stomatology of Shanghai Ninth People's Hospital affiliated to Shanghai Jiao Tong University School of Medicine. A total of 129 human mandibular premolars were collected, 69 of which were assigned to 3 groups (A1, B1 and C1).

Combined forms of Pb and its detoxification and absorption in Cladophora rupestris subcells.

This study aims to analyze the combined form, detoxification, and adsorption mechanism of Pb in Cladophora rupestris subcells. The chemical form analysis at different concentrations (0, 0.5, 1.

Feasibility of relatively low neoadjuvant radiation doses for locally advanced rectal cancer: A propensity score-matched analysis.

Background: Neoadjuvant chemoradiation therapy is part of the standard treatment of locally advanced rectal cancer (LARC). Although various options for modifying preoperative radiotherapy protocols have been researched and proposed, there is still no consensus as to the most appropriate dose regimen of neoadjuvant therapy for this disease.

Aim: To evaluate the effects of relatively low-dose radiation regimens on tumor regression and clinical outcomes in rectal cancer patients treated with neoadjuvant CRT followed by mesorectal excision.

Prognostic factors and patterns of recurrence after curative resection for patients with distal cholangiocarcinoma.

Background And Purpose: This study aimed to determine the prognostic factors and generate an atlas of a distribution of locoregional recurrence (LRR) in patients with distal cholangiocarcinoma (DCCA), after pancreatoduodenectomy (PD) without adjuvant radiotherapy.

Materials And Methods: 124 DCCA cases registered in our institutional database from 2006 to 2018 were analyzed retrospectively. The Cox proportional hazards model was used for multivariable analysis.

[Comparison of skeletal structure of temporomandibular joint through cone-beam CT between Angle ClassⅠ, Ⅱ, Ⅱ, Ⅲ malocclusion patients with permanent dentition].

Purpose: To compare characteristics of temporomandibular joint and related structures according to gender and Angle Ⅰ, Ⅱ, Ⅱ and Ⅲ class.

Methods: Cone-beam CT (CBCT) was performed in 123 patients with malocclusion, and three-dimensional reconstruction was performed with Mimics 19.0 software.

Fusion of Dendritic Cells and Cancer-Associated Fibroblasts for Activation of Anti-Tumor Cytotoxic T Lymphocytes.

Here we explored the fusion of dendritic cells (DCs), potent antigen-presenting cells that initiate primary immune responses, with cancer-associated fibroblasts (CAFs), which are a stromal component needed for tumor progression, with the aim of stimulating T cells to inhibit tumor growth. Dendritic cells from the bone marrow of BALB/c mice were co-cultured with CAFs from H22 mouse hepatoma cells. CAFs were found to express fibroblast activation protein and α-smooth muscle actin by flow cytometry, Western blotting and immunofluorescence.

An MOF-like Interpenetrated 2D Plus 2D to 3D Inorganic Grid Assembled by Linear Inorganic Pillars, Structures, and Properties in Supercapacitance.

Remarkable progresses regarding pure inorganic frameworks and metal-organic frameworks (MOF) have been made. However, pure inorganic frameworks with MOF-like grid structures are rarely reported due to the weakness of inorganic moiety as a long linear linker. We report herein a fascinating inorganic framework assembled by a [GeS] cluster node and a linear [-Cu-MS-Cu-] (M = Mo (1) and W (2)) inorganic pillar.

Concurrent Chemoradiotherapy in Curatively Resected Gallbladder Carcinoma: A Propensity Score-Matched Analysis.

Purpose: To compare overall survival (OS) between patients receiving radical resection followed by concurrent chemoradiotherapy (S+CCRT) and patients receiving radical resection only (S) for advanced resectable gallbladder carcinoma (GBC).

Methods And Materials: Ninety-four GBC patients with stage pT2-4, N0-1, and M0 consented to inclusion in a clinical database from June 2003 to July 2013. Patients who received S+CCRT were matched by propensity score with those who received S through nearest-neighbor matching, with a caliper width of 0.

Endobronchial ultrasound guided transbronchial needle aspiration combining with immunohistochemistry and genotype in lung cancer: A single-center, 55 cases retrospective study.

Objective: The purpose of this study was to evaluate the utility of EBUS-TNA for mediastinal mass or suspected lung cancer patients with mediastinal or hilar lymph node enlarged. Further to investigate the clinical value of EBUS-TBNA combining with immunohistochemistry and genotype in lung cancer.

Methods: A total of 55 patients with mediastinal, and/or hilar lymphadenopathy, and/or mediastinal mass previously detected by CT or PET/CT scan and who underwent EBUS-TBNA.

A nano-scale triangular ring cluster of indium-selenide: the structure and templating effect.

Different from the dominating supertetrahedral structure of InSe clusters, co-assembled nano-scale In33Se60 triangular ring clusters and wheel-shaped In18Se30 clusters have been found. The unusual second-sphere coordination templating effect of the Mn(dach) complexes and the central Mn(2+) ion is responsible for the formation of the triangular ring. The optical and electronic properties are discussed.

Fluorescence and energy transfer properties of heterometallic lanthanide-titanium oxo clusters coordinated with anthracenecarboxylate ligands.

Two 9-anthracenecarboxylate (9-AC) coordinated heterometallic TOC compounds, [Ln2Ti10O14(ClO4)2(O(i)Pr)14(9-AC)2(CH3CN)2]·2H2O, Ln = Nd 1() and Eu (2), along with two benzoate (bza) analogues, [Ln2Ti10O14(ClO4)2(O(i)Pr)14(bza)2(HO(i)Pr)2], Ln = Nd (3) and Eu (4), were prepared by one step in situ solvothermal synthesis, and characterized by single crystal analysis. To date, only about ten lanthanum-titanium oxo clusters have been reported. Except for two Ti28 clusters, the compounds are all small clusters (Ti ≤ 4).

Ion pair charge-transfer thiogermanate salts [MV]2Ge4S10·xSol: solvent induced crystal transformation and photocurrent responsive properties.

As most of the chalcogenidometalate anions are well-known electron-rich systems, design and preparation of ion pair compounds, by integrating an organic acceptor (A) with an inorganic chalcogenidometalate donor (D), are an attractive strategy to obtain new functional materials. We report herein the single-crystal structures and properties of three new ion pair charge-transfer (IPCT) compounds by incorporating thiogermanates with methylviologen (MV(2+), N,N'-dimethyl-4,4'-bipyridinium dication), [MV]2Ge4S10·xSol (Sol = solvent). Sharp and fast solvent-induced color changes and switchable fluorescence emission are observed for the compounds.