The fate of atenolol in wastewater treatment plants of representative densely urban agglomerations in China.

Atenolol (ATL) that can decrease heart rate and reduce renin release is extensively used in the treatment of hypertension, angina, and other diseases. ATL's popularity has therefore drawn attention to its environmental behavior and potential impacts. Wastewater treatment plants (WWTPs) are the main collection point for ATL entering the water environment, highlighting the necessity of studying its fate in the environment.

Effects of ethyl palmitate on the release of aroma compounds in propanediol-ethanol solution and its mechanisms.

Long-chain esters (LCEs) are known to affect aroma perception, but the mechanism of their effects remains unclear. In this study, ethyl palmitate (EP), an important LCE in flower absolute (OFFA), was selected as a target to identify its role and mechanism. The release characteristics of 10 aroma compounds from OFFA with and without EP were obtained by headspace gas chromatography mass spectrometry (HS-GC/MS) and olfactometry evaluation, respectively.

Extracellular vesicle-derived silk fibroin nanoparticles loaded with MFGE8 accelerate skin ulcer healing by targeting the vascular endothelial cells.

Background: Reduced supplies of oxygen and nutrients caused by vascular injury lead to difficult-to-heal pressure ulcers (PU) in clinical practice. Rapid vascular repair in the skin wound is the key to the resolution of this challenge, but clinical measures are still limited. We described the beneficial effects of extracellular vesicle-derived silk fibroin nanoparticles (NPs) loaded with milk fat globule EGF factor 8 (MFGE8) on accelerating skin blood vessel and PU healing by targeting CD13 in the vascular endothelial cells (VECs).

N-acetylcysteine attenuates the incidence of phlebitis induced by carbomer/vinorelbine gel.

Background: The high incidence and severe clinical manifestations of phlebitis pose a complex and urgent clinical challenge. The rapid and simple establishment of animal phlebitis models and the development of preventive strategies are crucial to resolving this problem.

Methods: In this study, we established such models by mixing vinorelbine ditartrate (VNR) and carbomer to form a sustained-release gel carrier, and then injected it around the veins rather than inside the vessels.

Agricultural waste biochar after potassium hydroxide activation: Its adsorbent evaluation and potential mechanism.

The agricultural waste (Goji branch) was pyrolyzed into biochars with one-step potassium hydroxide (KOH) activation under different processing conditions. The biochars were first characterized in structural features and functional groups and then evaluated for adsorptive performance with methylene blue as a model pollutant. Different adsorption models were applied to fit the adsorption process and reveal the possible mechanisms.

Efficacy of crown lengthening for restoration of maxillary anterior tooth defects.

Objective: The appearance of the gingival tissue around the teeth is essential in the aesthetics of the anterior maxillary region of the oral cavity. Abnormalities in symmetry and contour can significantly compromise the appearance of the natural or restored dentition, so the outcome is highly relevant to treatment choice. This study evaluated the efficacy of crown lengthening for restoration of maxillary anterior tooth defects.

ELAVL1 promotes LPS-induced endothelial cells injury through modulation of cytokine storm.

Sepsis is a life-threatening systemic organ dysfunction caused by the host's unregulated response to a widespread bacterial infection. Endothelial injury is a major pathophysiologic symptom of sepsis and is considered a critical factor in promoting the progression of disease severity. ELAV like RNA binding protein 1(ELAVL1) is a ubiquitously expressed RNA-binding protein that may play an important role during sepsis.

Genome-centric polyhydroxyalkanoate reconciliation reveals nutrient enriched growth dependent biosynthesis in Bacillus cereus IBA1.

Microbiological polyhydroxyalkanoates (PHAs) are rooted as the most promising bio-replacements of synthetic polymers. Inherent properties of these PHAs further expand their applicability in numerous industrial, environmental, and clinical sectors. To propel these, a new environmental, endotoxin free gram-positive bacterium i.

Synthesis of sulfur-containing benzo[]pyrrolo[2,1-][1,4]oxazine-3,9-diones: blue light promoted radical cyclization process.

The selective and controllable construction of spio-tricyclic skeletons through visible light promoted radical cyclization still remains challenging. Herein, a general and convenient protocol for the blue light-promoted radical-mediated cascade spiro-cyclization/Michael addition of -arylpropiolamides with thiophenols under metal-free conditions was developed. In this protocol, commercially available hydrochloric acid was employed as the cheap promoter and air as the sustainable oxidant.

A review on mechanistic understanding of microplastic pollution on the performance of anaerobic digestion.

Anaerobic digestion (AD) has emerged as a promising technology for diverting the organic waste from the landfills along with the production of clean energy. AD is a microbial-driven biochemical process wherein the plethora of microbial communities participate in converting the putrescible organic matter into biogas. Nevertheless, the AD process is susceptible to the external environmental factors such as presence of physical (microplastics) and chemical (antibiotics, pesticides) pollutants.

Extraction of Corn Bract Cellulose by the Ammonia-Coordinated Bio-Enzymatic Method.

This study explored a green and efficient method for cellulose extraction from corn bract. The cellulose extraction by the CHB (CHCOOH/HO/Bio-enzyme) method and the N-CHB (NH·HO-CHCOOH/HO/Bio-enzyme) method were compared and analyzed. The effect of ammonia pretreatment on cellulose extraction by bio-enzymatic methods was discussed.

Effect of different-sized bulking agents on nitrification process during food waste digestate composting.

Food waste digestate (FWD) disposal is a serious bottleneck in anaerobic digestion plants to achieve a circular bioeconomy. FWD could be recycled into nitrogen-rich compost; however, the co-composting process optimisation along with bulking agents is required to reduce nitrogen loss and unwanted gaseous emissions. In the present study, two different-sized bulking agents, namely, wood shaving (WS) and fine sawdust (FS), were used to investigate their impact on FWD composting performance along with the nitrogen dynamics.

Influence of inoculum-to-substrate ratio on biogas enhancement during biochar-assisted co-digestion of food waste and sludge.

High accumulation of volatile fatty acids (VFAs) is one of the major concerns during mesophilic anaerobic co-digestion of food waste (FW) and sewage sludge (SS). Therefore, improving the stability of the anaerobic digestion process could surpass quick acidification while accelerating methanogenesis. In this study, the suitability of biochar-assisted co-digestion was evaluated at different inoculum and substrate ratios (I/S ratios: 0.

Enhanced stability of food waste anaerobic digestion under low inoculum to substrate ratio by using biochar.

The influence of biochar on anaerobic digestion (AD) of organic waste have been widely studied. However, the effect of biochar on the mitigation of acidification and subsequently the stimulation of methanogenesis recovery during mono food waste (FW) digestion process under a low inoculum to substrate (I/S) ratio (i.e.

Regulation of acidogenic fermentation through exogenous additives for promoting carbon conversion of food waste in two-phase anaerobic system.

In this study, exogenous Megasphaera elsdenii inoculum and acetate supplementation were introduced at the acidogenic phase to regulate the acidogenic fermentation pathway and assess their effects on food waste (FW) carbon conversion in two-phase anaerobic digestion (AD) system. These two additives significantly accelerated organic removal efficiency and subsequently increased FW hydrolysis and acidogenesis by 16% and 35%, respectively. As expected, two exogenous additives promoted butyrate fermentation during FW acidogenesis.

Moderate potassium ferrate dosage enhances methane production from the anaerobic digestion of waste activated sludge.

The annual increase of waste activated sludge (WAS) has become an urgent problem to be solved in sewage plants worldwide. Anaerobic digestion (AD) of WAS is an attractive choice to maximize the resource utilization rate. Nevertheless, the disintegration of sludge complex polymers is difficult, resulting in a low bioconversion rate.

Hydrochar prepared from digestate improves anaerobic co-digestion of food waste and sewage sludge: Performance, mechanisms, and implication.

This work reported a new waste functionalization and utilization method, which use digestate to prepare hydrochar to improve methane production from food waste (FW) and sewage sludge (SS). Experimental results presented that 10 g/L hydrochar obtained the cumulative methane production of 133.11 ± 1.

Recent advances in conductive materials amended anaerobic co-digestion of food waste and municipal organic solid waste: Roles, mechanisms, and potential application.

Recently, conductive materials (i.e., carbon-based and iron-based materials) as a feasible and attractive approach have been introduced to anaerobic co-digestion (ACoD) system for promoting its performance and stability through direct interspecies electron transfer.

Radiation Dose Reduction and Surgical Efficiency Improvement in Endoscopic Transforaminal Lumbar Interbody Fusion Assisted by Intraoperative O-arm Navigation: A Retrospective Observational Study.

Objective: Endoscopic transforaminal lumbar interbody fusion (Endo-TLIF) has gained increasing popularity among spine surgeons. However, with the use of fluoroscopy, intraoperative radiation exposure remains a major concern. Here, we aim to introduce Endo-TLIF assisted by O-arm-based navigation and compare the results between O-arm navigation and fluoroscopy groups.

Injectable cartilage matrix hydrogel loaded with cartilage endplate stem cells engineered to release exosomes for non-invasive treatment of intervertebral disc degeneration.

Low back pain, mainly caused by intervertebral disc degeneration (IVDD), is a common health problem; however, current surgical treatments are less than satisfactory. Thus, it is essential to develop novel non-invasive surgical methods for IVDD treatment. Here, we describe a therapeutic strategy to inhibit IVDD by injecting hydrogels modified with the extracellular matrix of costal cartilage (ECM-Gels) that are loaded with cartilage endplate stem cells (CESCs).

Evaluations of biochar amendment on anaerobic co-digestion of pig manure and sewage sludge: waste-to-methane conversion, microbial community, and antibiotic resistance genes.

Effects of biochar on co-digestion of pig manure and dewatered sewage sludge under different total solids (TS) were investigated. Biochar could accelerate the start-up of methanogenesis and shorten the adaptation phase. At TS5%, the methane daily production in biochar group was 60.

Effect of biochar combined with a biotrickling filter on deodorization, nitrogen retention, and microbial community succession during chicken manure composting.

The high-nitrogen content and dense structure of poultry manure compost cause volatilization of N to ammonia (NH). This study evaluated the combined application of biochar and biotrickling filtration (BTF) to remove of odor in chicken manure mixed straw compost (w/w, 2.5:1).

The role of hygrodynamic resistance compared to biofilm formation in helping pathogenic bacteria dominate air-conditioning units recovered from odour problems.

We previsouly found that installing filters in odourous air-conditioning units (ACUs) to block the entry of skin squames could well tackle the odour problems. In this study, we revisited and sampled the ACUs installed with filters earlier to study the bacterial communities inside the ACUs using 16S amplicon sequencing. We identified 26 genera and found that the skin bacteria isolated in the previous work were absent in this study.