Publications by authors named "Liwen Du"

Objective: To compare the performance of radiologists when assisted by an S-detect system with that of radiologists or an S-detect system alone in diagnosing breast masses on US images in a dual-center setting.

Methods: US images were retrospectively identified 296 breast masses (150 benign, 146 malignant) by investigators at two medical centers. Six radiologists from the two centers independently analyzed the US images and classified each mass into categories 2 to 5.

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Rationale And Objectives: To construct a radiomics nomogram derived from multiparametric ultrasound (US) imaging using the SHapley Additive exPlanations (SHAP) method for the accurate identification of residual axillary lymph node metastases post-neoadjuvant chemotherapy (NAC) among patients with triple-negative breast cancer (TNBC).

Methods: A total of 405 consecutive patients with pathologically confirmed TNBC between 2016 and 2023 were recruited in the study and were divided into training (n = 284) and validation cohorts (n = 121). Radiomics features capturing detailed tumor characteristics were extracted from pre-NAC gray-scale US images at the locations of US-guided clip placement.

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Objective: To determine whether adding elastography strain ratio (SR) and a deep learning based computer-aided diagnosis (CAD) system to breast ultrasound (US) can help reclassify Breast Imaging Reporting and Data System (BI-RADS) 3 and 4a-c categories and avoid unnecessary biopsies.

Methods: This prospective, multicentre study included 1049 masses (691 benign, 358 malignant) with assigned BI-RADS 3 and 4a-c between 2020 and 2022. CAD results was dichotomized possibly malignant vs.

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Article Synopsis
  • A research study reviewed the impact of exercise on brain-derived neurotrophic factor (BDNF) levels in Alzheimer's disease models, highlighting conflicting results influenced by various factors like gender and age.
  • The analysis included 36 randomized controlled trials from 1196 initial studies, revealing a significant overall increase in BDNF levels due to exercise.
  • Specific types of exercise such as treadmill, swimming, and voluntary wheel running were particularly effective, with swimming showing the highest increase in BDNF levels within the hippocampus and cortex of Alzheimer's models.
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Background: Chlorfenapyr is used to kill insects that are resistant to organophosphorus insecticides. Chlorfenapyr poisoning has a high mortality rate and is difficult to treat. This article aims to review the mechanisms, clinical presentations, and treatment strategies for chlorfenapyr poisoning.

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  • A meta-analysis was conducted to evaluate the impact of exercise on various aspects of wellness in individuals with multiple sclerosis (MS), including balance, walking ability, fatigue, and overall quality of life.
  • The analysis included data from 40 studies and demonstrated that exercise resulted in significant improvements in balance (measured by BBS), walking endurance (assessed by 6MWT), fatigue levels, and quality of life metrics in MS patients.
  • Different types of exercises, especially resistance training and aerobic activities, were found to be effective, with resistance training showing the greatest positive effect on fatigue, suggesting that younger individuals with MS may experience more substantial benefits from exercising.
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Background: The accurate prediction of pathological complete response (pCR) in the breast and axillary lymph nodes (ALN) before neoadjuvant chemotherapy (NAC) is of utmost importance for the development of treatment strategies. We aim to construct a nomogram on ultrasound (US) and clinical-pathologic factors to predict breast and ALN pCR in node-positive triple-negative breast cancers (TNBCs).

Methods: Patients identified with TNBCs from institution 1 (n = 328) were used for training cohort and those from institution 2 (n = 192) were for validation cohort.

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  • A systematic review and meta-analysis were conducted to explore the impact of exercise on flow-mediated dilation (FMD) in people with type 2 diabetes mellitus (T2DM), revealing that exercise significantly improves FMD.
  • The analysis included 13 studies, indicating that high-intensity interval training (HIIT) was the most effective type of exercise, alongside recommendations for frequency and duration of workouts.
  • The results suggest that T2DM patients should aim for more than 3 exercise sessions per week, with each session lasting less than 60 minutes, and a goal of 180 minutes of exercise per week for optimal benefits.
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Intelligentization of materials and structures is an important trend. Herein, the stimuli-responsive 4D aerogel is used as a smart substrate for rapid reduction in tetracycline (TC) pollution, in which this smart stimuli-responsive substrate is designated as P4D. Its fourth dimension originates from stimuli-responsive characteristics with time evolution.

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Purpose: To determine whether the primary tumor features derived from conventional ultrasound (US) and contrast-enhanced US (CEUS) facilitate the prediction of positive axillary lymph nodes (ALNs) in breast cancer diagnosed as Breast Imaging Reporting and Data System (BI-RADS) category 4.

Methods: A total of 240 women with breast cancer who underwent preoperative conventional US, strain elastography, and CEUS between September 2016 and December 2019 were included. The multiple parameters of the primary tumor were obtained, and univariate and multivariate analyses were performed to predict positive ALNs.

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Objective: A growing body of research examining the effect of exercise on cognitive function in people with multiple sclerosis (MS), while findings of available studies were conflicting. We aimed to explore the effect of exercise on cognitive function in MS patients.

Methods: For this systematic review and meta-analysis, we searched PubMed, Web of Science, EBSCO, Cochrane, and Scopus electronic databases, through July 18, 2022.

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Background: Heatstroke is the most hazardous heat-related illness and has a high fatality rate. We investigated whether glutamine supplementation could have a protective effect on heatstroke rats.

Methods: Twenty-five 12-week-old male Wistar rats (weight 305±16 g) were randomly divided into a control group (n=5), heatstroke (HS) group (n=10), and heatstroke+glutamine (HSG) group (n=10).

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Background: High bifurcation of the deep femoral artery (DFA) is rare in clinical practice, and patients with this variation are less likely to receive venoarterial extracorporeal membrane oxygenation (V-A ECMO) treatment. Therefore, the method by which V-A ECMO is introduced in patients with vascular variation is very important.

Case Presentation: A 52-year-old male patient had ST elevation myocardial infarction due to coronary heart disease.

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Aims: The impact of neoadjuvant therapy on the functional outcome of patients with resectable rectal cancer is still controversial. The aim of the present study was to explore the effects of neoadjuvant therapy on anorectal function (ARF), urinary function and sexual function in relevant patients.

Materials And Methods: PubMed, Embase, Web of Science and the Cochrane Library were searched systematically.

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Objective: To study the effects of modified Lamaze breathing on abdominal pain experienced during colonoscopy.

Methods: Eighty-five patients who underwent common colonoscopy at our hospital between March 2021 and May 2021 were selected and randomly divided into the Lamaze group ( = 40) and a control group ( = 45). Their basic clinical information was collected, and the bowel cleanliness, the time for the endoscope to reach the ileocecal junction, and the degree of abdominal pain of the two groups were compared.

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Objective: Vitamin D (Vit D) regulates calcium and phosphate metabolism and helps to maintain otolith organ function. Residual dizziness (RD) is one of the most common complications after the successful treatment of benign paroxysmal positional vertigo (BPPV). Various theories have been suggested to explain the cause of RD, and otolith organ disorder is the most evident cause of RD.

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Objective: This study aimed to develop a radiomics nomogram that incorporates radiomics, conventional ultrasound (US) and clinical features in order to differentiate triple-negative breast cancer (TNBC) from fibroadenoma.

Methods: A total of 182 pathology-proven fibroadenomas and 178 pathology-proven TNBCs, which underwent preoperative US examination, were involved and randomly divided into training ( = 253) and validation cohorts ( = 107). The radiomics features were extracted from the regions of interest of all lesions, which were delineated on the basis of preoperative US examination.

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Novel preparation of molybdenum modified bimetallic micro-mesoporous catalyst was proposed innovatively to conduct catalytic fast pyrolysis of enzymatic hydrolysis lignin. The optimal catalytic characterization of the prepared catalyst was attributed to appropriate porous structure, the interaction between zeolite support and metal species, and the synergetic and stable mechanism of bimetallic active sites. With the incorporation of metal species into micro-mesoporous catalyst, the distribution of active sites experienced a regulation, which contributed to MAHs production and cracking of oxygen-containing substances.

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Objective: To evaluate the diagnostic performance of contrast-enhanced ultrasound (CEUS) combined with conventional ultrasound of axillary lymph nodes (ALNs) in predicting metastatic ALNs in patients with breast cancer.

Methods: This retrospective study included 259 patients with breast cancer who underwent conventional ultrasound and CEUS. The parameters and patterns evaluated on conventional ultrasound included short axis diameter (S), long axis/short axis (L/S) ratio, cortical thickness, resistive index (RI), lymph node (LN) morphology of greyscale ultrasound, hilum and vascular pattern.

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