Publications by authors named "Livio Baron"
Mol Cell Biol
October 2007
Article Synopsis
- The expression of retinoblastoma protein (pRb) and cyclin D3 increases significantly during skeletal myoblast differentiation, with pRb helping to stabilize cyclin D3.
- Cyclin D3 is quickly broken down in proliferating myoblasts, and this degradation is prevented when pRb is present, aiding muscle-specific gene expression.
- The study illustrates a new interaction between pRb and cyclin D3, showing that their complex formation blocks the phosphorylation that normally leads to cyclin D3 degradation, highlighting pRb's role in muscle cell differentiation.
