Efflux pump inhibition controls growth and enhances antifungal susceptibility of species complex.

To evaluate the inhibition of efflux pumps by using promethazine (PMZ) as a strategy to control species complex (FSSC). The susceptibility of FSSC strains to PMZ and the interaction between PMZ and antifungals were evaluated. The efflux pump activity was confirmed by flow cytometry with rhodamine 6G.