Publications by authors named "Livia Mara Vitorino da Silva"
The Th2 Response and Alternative Activation of Macrophages Triggered by Is Linked to Increased Morbidity and Mortality Due to Cryptococcosis in Mice.
J Fungi (Basel)
September 2023
Cryptococcosis is a systemic mycosis that causes pneumonia and meningoencephalitis. Strongyloidiasis is a chronic gastrointestinal infection caused by parasites of the genus Cryptococcosis and strongyloidiasis affect the lungs and are more prevalent in the same world regions, i.e.
View Article and Find Full Text PDFRandomized, phase 1/2, double-blind pioglitazone repositioning trial combined with antifungals for the treatment of cryptococcal meningitis - PIO study.
Contemp Clin Trials Commun
June 2021
Article Synopsis
- - The study investigates the effectiveness and safety of pioglitazone (PIO), an antidiabetic drug, in combination with standard antifungal treatments for cryptococcosis, aiming to improve patient outcomes since current treatments have high toxicity and limited availability in Brazil.
- - Conducted as a phase 1/2 randomized, double-blind, placebo-controlled trial, patients in Belo Horizonte will be divided into three groups receiving either a placebo, PIO 15 mg/day, or PIO 45 mg/day during treatment to assess changes in mortality, fungal burden, and side effects over a follow-up period of 60 days.
- - The research aims to establish PIO as a beneficial adjuvant therapy, potentially increasing survival rates
Characterization and molecular epidemiology of strains resistant to beta-lactams isolated from the milk of cows diagnosed with subclinical mastitis.
Vet World
December 2019
Background And Aim: The term ESKAPE, recognized by the WHO, is an acronym, which refers to the pathogens , , , , , and spp., which is extremely virulent and multidrug-resistant. Although the term is used to designate nosocomial pathogens, in a milking environment, strains of Methicillin-resistant have been isolated from cattle diagnosed with clinical and subclinical mastitis.
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