Causes of death in individuals with lifetime major depression: a comprehensive machine learning analysis from a community-based autopsy center.

Background: Depression can be associated with increased mortality and morbidity, but no studies have investigated the specific causes of death based on autopsy reports. Autopsy studies can yield valuable and detailed information on pathological ailments or underreported conditions. This study aimed to compare autopsy-confirmed causes of death (CoD) between individuals diagnosed with major depressive disorder (MDD) and matched controls.

Microcephaly measurement in adults and its association with clinical variables.

Objective: To establish a microcephaly cut-off size in adults using head circumference as an indirect measure of brain size, as well as to explore factors associated with microcephaly via data mining.

Methods: In autopsy studies, head circumference was measured with an inelastic tape placed around the skull. Total brain volume was also directly measured.