Publications by authors named "Livia Bertazzo Sacilotto"
Article Synopsis
- The use of antiretroviral therapy (ART) to treat HIV/AIDS can lead to side effects like lipodystrophy, which involves changes in body fat distribution and increases the risk of cardiovascular disease.
- Adipocytokines, proteins that affect metabolic processes, have altered levels in people living with HIV/AIDS (PLWHA), regardless of their treatment status, and are linked to metabolic syndrome and cardiovascular issues.
- A study with 110 individuals, including PLWHA and a control group, compared body composition and biochemical markers related to adipocytokines, revealing significant correlations between certain cytokines and metabolic parameters across genders.
HIV-associated lipodystrophy syndrome (HALS) is characterized by body fat redistribution as a consequence of the antiretroviral therapy (ART) introduction, associated with an increased risk of cardiovascular disease development. Subjective diagnosis, classified between three subtypes according to the body region on which fat is lost and/or accumulated, named lipoatrophy, lipohypertrophy, and mixed lipodystrophy, is possibly accompanied with metabolic alterations. Forty people living with HIV/AIDS (PLHA), with clinical diagnosis of HALS and from both genders, were assessed.
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