The study aimed to explore how cardiovascular risk factors like age, BMI, and blood pressure relate to the thickness of various retinal layers, like the ganglion cell-inner plexiform layer (GCIPL).
The research included data from two rounds of the Tromsø Study, measuring retinal thickness and excluding individuals with diabetes or glaucoma, ultimately analyzing 8,288 participants cross-sectionally and 2,595 longitudinally.
The findings revealed that GCIPL thickness was notably impacted by age and BMI, with significant relationships identified for blood pressure, emphasizing that weight and blood pressure are important factors for modifying retinal health.