A novel polyhedral oligomeric silsesquioxane-based hybrid monolith as a sorbent for on-line in-tube solid phase microextraction of bisphenols in milk prior to high performance liquid chromatography-ultraviolet detection analysis.

An on-line in-tube solid-phase microextraction (in-tube SPME) coupled with high-performance liquid chromatography (HPLC) method was proposed based on a novel polyhedral oligomeric silsesquioxane (POSS)-hybrid monolith for the determination of four bisphenols (BPs) in milk. The monolith was synthesized using acrylamide (AM) and monomethacrylate-functionalized POSS (mono-MA-POSS) as functional monomers to copolymerize with ethylene dimethacrylate (EDMA). Due to the abundant hydrogen bonding, π-π and hydrophobic interaction sites, the synthetic monolith displayed satisfying extraction performance for target BPs.

Application of the liquid-liquid dispersed microextraction based on phase transition behavior of temperature sensitive polymer to rapidly detect 5 BPs in food packaging.

In this paper, temperature sensitive polymer p(MAH-β-CD-co-NIPAM) was used as extraction in DLLME, because its phase transition behavior can be observed at room temperature due to Hofmeister and non-co-solvent effect. The whole pretreatment process is simple and fast, and the extraction process did not require dispersant to assist dispersion and centrifugation to collect the adsorbent. A new analytical method based on DLLME coupled with HPLC-UV was developed to detect five types of BPs in milk and take-out packaging.