Publications by authors named "Liuji Qiu"

Article Synopsis
  • The study investigates the effects of dexmedetomidine, used during colorectal cancer surgery, on patient survival rates and recurrence-free survival.
  • It involved 76 patients, with a comparison between those who received dexmedetomidine and those who did not, showing significant improvements in survival for the dexmedetomidine group.
  • The findings suggest that using dexmedetomidine in surgery could enhance long-term outcomes and reduce cancer recurrence for colorectal cancer patients.
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Thrombolytic therapy or percutaneous coronary intervention for myocardial infarction often cause myocardial ischemia/reperfusion injury (MIRI) and poor prognosis of patients. This study aimed to explore the protective effect and potential mechanism of hydromorphone hydrochloride (HH) on MIRI. Fifty Sprague-Dawley male rats were randomly divided into Sham group, I/R group, HH-pre group, HH-post group, and HH-pre + post group.

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Objective: Sufentanil is the most common drug in clinical practice for the treatment of ischemic heart disease. This study is to investigate the protective mechanism of sufentanil on rat myocardial ischemia-reperfusion (I/R) injury.

Methods: A rat I/R model was established by ligating the left anterior descending coronary artery.

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Morphine is generally used to treat chronic pain in clinic. But long-term use of morphine can inevitably induce analgesic tolerance and hyperalgesia. Caveolin-1 is reported to affect morphine-mediated signaling transduction.

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Objective of this study was to investigate the sedative and hypnotic effects of palmatine and to observe whether its mechanism is related to 5-hydroxytryptamine (5-HT) and GABA. The sedative and hypnotic effects of palmatine on mice were observed with mouse autonomic activity test, direct sleep test, pentobarbital sodium in suprathreshold and subthreshold dose sleep test. The content of GABA and 5-HT in brain homogenate was determined by ELISA  method.

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