Markers for predicting the severity of acute pancreatitis.

Objective: Aim: To identify markers for predicting the severity of acute pancreatitis and the possible development of pancreatic necrosis.

Patients And Methods: Materials and Methods: Prospective analysis of 81 patients with moderate and severe acute pancreatitis while performing correlation analysis, building a logistic regression model.

Results: Results: A direct correlation of medium strength between sFGL2 and the following parameters was found D-dimer (R=0.

CHANGES ANALYSIS OF THE HEPATOCYTE APOPTOSIS MARKERS LEVELS IN MALIGNANT OBSTRUCTIVE JAUNDICE COMPLICATED BY CHOLANGITIS.

Objective: The aim: To evaluate changes in the levels of hepatocyte apoptosis markers in malignant obstructive jaundice (MOJ) depending on the performance of preoperative biliary decompression (PBD) and the severity degree of primary ascending cholangitis (PAC).

Patients And Methods: Materials and methods: 136 patients with MOJ complicated by cholangitis were included in the study: group A (n=84) - patients who underwent PBD; group B (n=52) - patients without PBD. The level of CASP3 and Bcl-2 (Human Bcl-2(B-cell Leukemia/Lymphoma 2) in blood serum and bile was assessed according to the principle of Sandwich-ELISA.