Publications by authors named "Liudmyla Syzova"
Objective: The aim: To analyze the incidence of Hepatitis A in Ukraine and Poltava region and to study the clinical and epidemiological features of the course of Hepatitis A in adult patients.
Patients And Methods: Materials and methods: The course of HA in 96 hospitalized patients was analyzed. The diagnosis of HA was established on the basis of clinical and epide¬miological data and confirmed by the results of laboratory studies (serological and molecular biological).
Objective: The aim: To analyze the current views on diagnosis and management of infectious mononucleosis in children. The purpose of our work is also a comparative characteristic of the incidence of infectious mononucleosis in Ukraine and the city of Poltava (2006-2022).
Patients And Methods: Materials and methods: The data of scientific literature have been analyzed, using the bibliosemantic method of study.
Objective: The aim: To study the clinical and laboratory characteristics of measles, as well as to compare the course of this disease in vaccinated and unvaccinated children in the Poltava region (Ukraine).
Patients And Methods: Materials and methods: 104 inpatients with measles were examined: vaccinated (n=27) and unvaccinated (n=77). The patient examination program included: assessment of complaints and anamnestic data obtained by questioning (during admission to hospital treatment, during treatment and after discharge) and detailed analysis of medical records (Form № 003/γ), physical examination, general clinical study of peripheral blood.
Objective: The aim: To study the clinical and laboratory characteristics of measles, as well as to compare the course of this disease in vaccinated and unvaccinated children in the Poltava region (Ukraine).
Patients And Methods: Materials and methods: 104 inpatients with measles were examined: vaccinated (n=27) and unvaccinated (n=77). The patient examination program included: assessment of complaints and anamnestic data obtained by questioning (during admission to hospital treatment, during treatment and after discharge) and detailed analysis of medical records (Form № 003/у), physical examination, general clinical study of peripheral blood.
Objective: The aim: Of the paper is to analyze the current views on diagnosis and management of diphtheria in children.
Patients And Methods: Materials and methods: The data of scientific literature have been analyzed, using the bibliosemantic method of study.
Conclusion: Conclusions: The specific prophylaxis is recommended to prevent the infection.
Objective: The aim: Is to study the efficacy of influenza vaccination for individuals with polymorphism Arg753Gln of TLR-2 gene, Leu412Phe of TLR-3 gene, and Asp299Gly of TLR-4 gene.
Patients And Methods: Materials and methods: 66 people with mutant genotypes and normal distribution of alleles of TLR-2, TLR-3, TLR-4 genes, aged 18-63, were inoculated with anti-influenza vaccine. The genotyping of Arg753Gln polymorphic site of TLR-2, Asp299Gly of TLR-4, and Leu412Phe of TLR-3 gene was carried out by polymerase chain reaction with oligonucleotide primers usage.
Objective: The aim: To analyze the epidemiological data and clinical course of pneumonia as a complication of influenza in the Poltava region, depending on the etiological agent.
Patients And Methods: Materials and methods: We have analysed the data of the official reporting documentation provided by the State Institution "Poltava Regional Laboratory Center of the Ministry of Health of Ukraine" and the chart of patients with a laboratory confirmed diagnosis of influenza who were in inpatient treatment at the Poltava Regional Clinical Infectious Hospital (PRCIH) in 2016-2018 years. In more detail, we examined 95 patients with pneumonia, which complicated the course of the flu.
Objective: Introduction: HIV-infection and chronic hepatitis C is of great concern of current infectology. The paper is aimed at the study of the prevalence of the of TLR4 gene Gly and TLR7 gene Leu polymorphic alleles among patients with HIV/HCV-coinfection in general and with regard to gender, as well as to determine their role in the development of the infection.
Patients And Methods: Materials and methods: To achieve the objective of the research a cohort and case-control study has been carried out.
Objective: The aim of the research is to study the prevalence and to determine the prognostic significance of polymorphism ARG753GLN of the TLR-2 gene, Leu412Phe of TLR-3, Asp299Gly of TLR-4 in influenza.
Patients And Methods: Materials and methods: 112 patients with influenza were examined (63 patients with uncomplicated course and 49 with influenza-associated pneumonia). The genotyping of the polymorphic site of ARG753GLN of the TLR-2 gene, Asp299Gly of the TLR-4 gene, and Leu412Phe of the TLR-3 gene was carried out by polymerase chain reaction using oligonucleotide primers.