Publications by authors named "Liudmyla A Vygivska"

Based on the analysis of information from available sources of scientific literature, the article provides an overview of the problem of abnormal uterine bleeding and its causes. Preservation of women's reproductive health is an urgent problem of the whole world. AUB is a debilitating symptom that affects a large number of women and one of the most common gynecological abnormalities.

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Article Synopsis
  • The study aimed to investigate the hormonal profiles of women experiencing abnormal uterine bleeding (AUB) alongside other extragenital disorders, comparing them to healthy counterparts.
  • Among the 100 women studied, significant hormonal variations were noted, including lower levels of FSH and LH in those with specific uterine pathologies, while estradiol levels were found to be elevated in a majority of affected women.
  • Additionally, there was a notable increase in leptin levels among the patients, a correlation with BMI and estradiol, and a high prevalence of vitamin D deficiency, suggesting complex hormonal interactions in women with AUB and related conditions.
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Objective: The aim: To determine the features of the impact of preeclampsia on the development of cardiovascular disorders in women in the future.

Patients And Methods: Materials and methods: The study involved an assessment of literary sources, which were published mainly in the last five years, using scientometric and specialized databases Pubmed, Science direct, Scopus, Web of Science, Google Scholar and V.I.

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Objective: The aim: According to the literature sources to summarize statistics on the prevalence of intrauterine infection and its impact on pregnancy and the condition of newborns at the present stage.

Patients And Methods: Materials and methods: The article analyzes 35 literature sources (scientific publications) from 2000 to 2021, indexed in international scientometric database and covers the incidence of intrauterine infections in countries with different income levels, as well as their impact on pregnancy, childbirth and the condition of newborns.

Conclusion: Conclusions: The main task of obstetrics and gynecology at the present stage is to reduce reproductive losses, which necessitates further study of the etiology of IUI, especially in low- and middle-income countries.

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Objective: The aim: On the basis of literature data, as well as a clinical case study, to assess the state of the problem of abnormal invasion of the placenta in obstetrics at the present stage.

Patients And Methods: Materials and methods: Based on the materials of the world's leading citation databases (MEDLINE, EMBASE, Cochrane), a brief review of the literature data over the past 5 years is presented, dedicated to the issues of abnormal placental invasion. The possibilities of a complex of diagnostic studies and clinical management of women with an anomaly of placenta attachment are considered.

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Objective: The aim of this study was to investigate the relation between urinary TGF-β1, urinary VEGF and renal scarring resulted from VUR.

Patients And Methods: Materials and methods: This study included 141 patients with VUR and 34 healthy sex and age matched children. The statistical analysis consisted of descriptive statistical parameters, KruskalWallis, Mann-Whitney tests and ROC analysis.

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Objective: The aim: To characterize the course of the most common perinatal infections on the basis of assessment of the literature data.

Patients And Methods: Materials and methods: This article provides an assessment of 125 literature sources submitted to PubMed, Medline, Cochrane Library, CyberLeninka, Google Scholar and V.I.

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Objective: The aim: To summarize the literature data on abnormal uterine bleeding in adolescents.

Patients And Methods: Materials and methods: This article presents an assessment of 32 literary sources from 2003 to 2018, which raise the issues of etiology and pathogenesis of abnormal uterine bleeding in adolescents. Abnormal uterine bleeding in adolescents (AUBA) is a risk factor for disorders of menstrual and generative function, hormone-related abnormalities in the reproductive age.

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The Aim: To study the impact of emergent infections (human herpesvirus type 6) on the fetal state.

Materials And Methods: The study involved examination of 90 pregnant women in the 2nd and 3rd trimesters of gestation (Group 1 (25 pregnant) consisted of patients with a viral infection, CMV carriers, Group 2 (25 pregnant) included women with a viral infection, herpes simplex virus types 1/2, Group 3 amounted for 20 patients with a viral infection, herpes simplex virus type 6, Group 4 comprised 20 patients with normal pregnancy and no signs of infection. Concentration of IgM and IgG to herpes simplex virus types 1/2, IgM and IgG to herpesvirus type 6 in venous blood of the pregnant was determined by enzyme-immunoassay.

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