Publications by authors named "Liudmila Ya Rozhinskaya"
Article Synopsis
- The study aimed to investigate how vitamin D metabolism differs in patients with active acromegaly compared to healthy individuals, particularly after administering cholecalciferol.
- In the study, 34 adults with acromegaly and a control group of 30 healthy adults received 150,000 IU of cholecalciferol, with various serum vitamin D metabolites assessed before and after treatment.
- Results indicated lower baseline and follow-up vitamin D levels in acromegaly patients, along with altered vitamin D metabolite production, suppressed parathyroid hormone levels, and a distinctive response to cholecalciferol compared to the control group.
Due to the high prevalence of low vitamin D levels in the overwhelming majority of regions of the world and discovery of extra-skeletal effects of vitamin D, the issue of maintaining adequate levels of vitamin D in the blood remains extremely relevant, especially in people with high risk of severe deficiency. To date, few studies have been performed on the features of vitamin D metabolism in disorders such as hypercorticism and acromegaly. However, vitamin D deficiency in such patients, according to available literature, may be more widespread and more pronounced than in general population.
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