Publications by authors named "Liuan Chen"
Article Synopsis
- SARS-CoV-2 is known for its rapid mutations, which allow it to evade neutralizing antibodies, a challenge highlighted by the reduced effectiveness of the antibody UT28K against the Omicron BA.1 variant.
- Researchers designed a modified version called UT28K-RD, targeting specific mutations to restore its neutralizing capability against Omicron BA.1, and validated its effectiveness through various lab experiments.
- The study showcases the successful design of antibodies tailored to combat viral mutations and suggests a promising direction for developing new treatments for highly mutable viruses like SARS-CoV-2.
