Publications by authors named "Liu-guo Pan"
The mechanism of miR-16-5p protection on LPS-induced A549 cell injury by targeting CXCR3.
Artif Cells Nanomed Biotechnol
December 2019
Objective: To study the effect of miR-16-5p on lung cancer cell injury and apoptosis, and its mechanism.
Methods: LPS induced lung cancer cell A549 injury; qRT-PCR method was applied to detect the expression of miR-16-5p and CXCR3 in A549 cells. Con (without LPS treatment), LPS + miR-NC group (transfected negative control samples), LPS + miR-16-5p group (transfected miR-16-5p mimics); LPS + si-NC group (transfected negative control samples), LPS + si-CXCR3 group (transfected si-CXCR3); LPS + miR-16-5p + pcDNA3.
Article Synopsis
- - The study investigates how microRNA-1224 (miR-1224) affects oxidative stress in liver cells (hepatocytes) induced by hydrogen peroxide (H₂O₂), aiming to uncover the mechanisms involved.
- - Researchers used various methods, including quantifying miR-1224 and hepatocyte growth factor (HGF) levels, to assess how altering miR-1224 expression impacts cell survival and apoptosis under oxidative stress.
- - Results show that reducing miR-1224 levels protects liver cells from damage caused by H₂O₂ by enhancing HGF expression, suggesting miR-1224's potential as a therapeutic target for liver injuries.
[A study on individual mandibular prostheses according to 3D reconstruction of CT images and CNC simulation method].
Zhongguo Yi Liao Qi Xie Za Zhi
March 2007
The new method of manufacturing individual mandibular prostheses, in combination with CT data and CNC technique, can duplicate bone tissues accurately, and can have the individual mandibular prosthesis made to order, and repair the mandibular defect (especially the lager mandibular segmental defect).
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