Publications by authors named "Liu-Sheng Lai"
Differential expression of transfer RNA-derived small RNAs in IgA nephropathy.
Medicine (Baltimore)
November 2020
Background: IgA nephropathy (IgAN) is one of the most common forms of primary glomerulonephritis. Recent studies have indicated that small noncoding RNAs, such as tRNA-derived small RNAs (tsRNAs), might be novel biomarkers for glomerulonephritis. We therefore investigated the potential roles and possible functions of the tsRNAs in IgAN.
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- - Bladder cancer is a prevalent and serious cancer affecting the urinary system, with current treatments including surgery, radiation, and chemotherapy, but there's a pressing need for new therapeutic targets to improve patient outcomes.
- - The study identified RAB38 as a protein linked to advanced bladder cancer features, such as higher stages and likelihood of recurrence, with its depletion leading to reduced cancer cell growth and movement.
- - Overall, the findings suggest that RAB38 plays a crucial role in bladder cancer progression, making it a potential new target for treatment strategies.