Publications by authors named "Liu-Kuo Ying"

Breast cancer is a leading cause of mortality among women in Taiwan and globally. Non-invasive imaging methods, such as mammography and ultrasound, are critical for early detection, yet standalone modalities have limitations in regard to their diagnostic accuracy. This study aims to enhance breast cancer detection through a cross-modality fusion approach combining mammography and ultrasound imaging, using advanced convolutional neural network (CNN) architectures.

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Background And Objectives: Chest X-ray (CXR) images are commonly used to diagnose respiratory and cardiovascular diseases. However, traditional manual interpretation is often subjective, time-consuming, and prone to errors, leading to inconsistent detection accuracy and poor generalization. In this paper, we present deep learning-based object detection methods for automatically identifying and annotating abnormal regions in CXR images.

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Article Synopsis
  • Spinal conditions like fractures and herniated intervertebral discs (HIVDs) can be tough to diagnose due to similar symptoms, making accurate differentiation vital for treatment and anesthesia planning.
  • A Support Vector Machine (SVM) model was developed to distinguish between spinal fractures and HIVDs using factors such as age, gender, and pain scores, analyzed on a dataset of 199 patients.
  • The SVM model demonstrated high precision (92.1% for fractures, 91.2% for HIVDs) and overall accuracy of 92%, identifying age and pain scores as key predictors, suggesting the model's potential for enhancing preoperative evaluations.
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Early detection of prostate cancer (PCa) and benign prostatic hyperplasia (BPH) is crucial for maintaining the health and well-being of aging male populations. This study aims to evaluate the performance of transfer learning with convolutional neural networks (CNNs) for efficient classification of PCa and BPH in transrectal ultrasound (TRUS) images. A retrospective experimental design was employed in this study, with 1380 TRUS images for PCa and 1530 for BPH.

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Background: Dental panoramic imaging plays a pivotal role in dentistry for diagnosis and treatment planning. However, correctly positioning patients can be challenging for technicians due to the complexity of the imaging equipment and variations in patient anatomy, leading to positioning errors. These errors can compromise image quality and potentially result in misdiagnoses.

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This study focuses on overcoming challenges in classifying eye diseases using color fundus photographs by leveraging deep learning techniques, aiming to enhance early detection and diagnosis accuracy. We utilized a dataset of 6392 color fundus photographs across eight disease categories, which was later augmented to 17,766 images. Five well-known convolutional neural networks (CNNs)-efficientnetb0, mobilenetv2, shufflenet, resnet50, and resnet101-and a custom-built CNN were integrated and trained on this dataset.

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Convolutional neural networks (CNNs) have shown promise in accurately diagnosing coronavirus disease 2019 (COVID-19) and bacterial pneumonia using chest X-ray images. However, determining the optimal feature extraction approach is challenging. This study investigates the use of fusion-extracted features by deep networks to improve the accuracy of COVID-19 and bacterial pneumonia classification with chest X-ray radiography.

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According to the Health Promotion Administration in the Ministry of Health and Welfare statistics in Taiwan, over ten thousand women have breast cancer every year. Mammography is widely used to detect breast cancer. However, it is limited by the operator's technique, the cooperation of the subjects, and the subjective interpretation by the physician.

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Background: Dividing liver organs or lesions depicting on computed tomography (CT) images could be applied to help tumor staging and treatment. However, most existing image segmentation technologies use manual or semi-automatic analysis, making the analysis process costly and time-consuming.

Objective: This research aims to develop and apply a deep learning network architecture to segment liver tumors automatically after fine tuning parameters.

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Chest X-ray (CXR) is widely used to diagnose conditions affecting the chest, its contents, and its nearby structures. In this study, we used a private data set containing 1630 CXR images with disease labels; most of the images were disease-free, but the others contained multiple sites of abnormalities. Here, we used deep convolutional neural network (CNN) models to extract feature representations and to identify possible diseases in these images.

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Intracerebral hemorrhage (ICH) is a common and severe neurological disorder associated with high morbidity and mortality rates. Despite extensive research into its pathology, there are no clinically approved neuroprotective treatments for ICH. Increasing evidence has revealed that inflammatory responses mediate the pathophysiological processes of brain injury following ICH.

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Background: Metal artifact reduction (MAR) techniques can improve metal artifacts of computed tomography (CT) images.

Objective: This work focused on conducting a quantitative analysis to compare the effectiveness of four commercial MAR techniques on three types of metal implants (hip implant, spinal implant, and dental filling) with a self-made acrylic phantom.

Methods: A cylindrical phantom was made from acrylic with a groove in the middle, and then three types of metal implants were placed in the groove.

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A metal implant was placed in an acrylic phantom to enable quantitative analysis of the metal artifact reduction techniques used in computed tomography (CT) scanners from three manufacturers. Two titanium rods were placed in a groove in a cylindrical phantom made by acrylic, after which the groove was filled with water. The phantom was scanned using three CT scanners (Toshiba, GE, Siemens) under the abdomen CT setting.

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Background: Coronary artery disease (CAD) remains the leading cause of death worldwide. Currently, cardiac multi-detector computed tomography (MDCT) is widely used to diagnose CAD. The purpose in this study is to identify informative and useful predictors from left ventricular (LV) in the early CAD patients using cardiac MDCT images.

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Purpose: A novel diagnostic method using the standard deviation (SD) value of apparent diffusion coefficient (ADC) by diffusion-weighted (DWI) magnetic resonance imaging (MRI) is applied for differential diagnosis of primary chest cancers, metastatic tumors and benign tumors.

Materials And Methods: This retrospective study enrolled 27 patients (20 males, 7 female; age, 15-85; mean age, 68) who had thoracic mass lesions in the last three years and underwent an MRI chest examination at our institution. In total, 29 mass lesions were analyzed using SD of ADC and DWI.

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Background: We report our experience with patients who had acquired immunodeficiency syndrome (AIDS) and who presented with signs and symptoms suggesting acute appendicitis.

Methods: Observational data are documented for 9 patients with AIDS who underwent surgery for acute appendicitis.

Results: Of the 9 patients, 6 (66.

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