Publications by authors named "Liu-Jin Hou"
Background: Acute-on-chronic liver failure (ACLF) patients have high mortality in a short period of time. This study aimed to compare the prognosis of transplanted ACLF patients to that of nontransplanted ACLF patients and decompensated cirrhosis recipients.
Methods: Clinical data of 29 transplanted ACLF patients, 312 nontransplanted ACLF patients, and 60 transplanted decompensated cirrhosis patients were retrospectively collected.
Article Synopsis
- Immune checkpoint inhibitors, like toripalimab, are becoming popular in treating solid tumors, including liver cancer (HCC).
- The safety of these inhibitors before or after liver transplant is still unclear, with previous reports mainly focusing on posttransplant rejection issues.
- In a case study, a patient who received toripalimab before liver transplant experienced severe acute hepatic necrosis, suggesting a potential link to immune rejection triggered by the treatment.