Novel benzothiazole-based fluorescent probe for efficient detection of Cu/S and Zn and its applicability in cell imaging.

Background: In recent years, environmental pollution has been increasing due to the excessive emission of toxic ions, which has caused serious harm to human health and ecological environment. There are various methods for detecting Cu, S and Zn, but the traditional ion detection methods have obvious disadvantages, such as poor selectivity and long detection time. Therefore, it is still crucial to develop simple, efficient and rapid detection methods.

Room temperature thermal rectification in suspended asymmetric graphene ribbon.

Thermal rectifiers are essential in optimizing heat dissipation in solid-state devices to enhance energy efficiency, reliability, and overall performance. In this study, we experimentally investigate the thermal rectification phenomenon in suspended asymmetric graphene ribbons (GRs). The asymmetry within the graphene is introduced by incorporating periodic parallel nanoribbons on one side of the GR while maintaining the other side in a pristine form.

Characteristics and emissions of isoprene and other non-methane hydrocarbons in the Northwest Pacific Ocean and responses to atmospheric aerosol deposition.

Field investigations in the Northwest Pacific Ocean were carried out to determine the distributions of marine and atmospheric non-methane hydrocarbons (NMHCs), sources and environmental effects. We also conducted deck incubation experiments to investigate the effects of atmospheric aerosol deposition on NMHCs production. The marine NMHCs displayed an increasing trend from the South Equatorial Current to the Oyashio Current.

Design and synthesis of dual cathepsin L and S inhibitors and antimetastatic activity evaluation in pancreatic cancer cells.

Currently, the migration and invasion of cancer cells remain the main factors of poor prognosis in the majority of cancer patients. Developing an effective antimetastatic agent is crucial for cancer therapy. Our recent research revealed that Cat L and S are expressed concurrently in metastatic pancreatic cancer cells.

Validation and derivation of short-term prognostic risk score in acute decompensated heart failure in China.

Background: Few prognostic risk scores (PRSs) have been routinely used in acute decompensated heart failure (ADHF). We, therefore, externally validated three published PRSs (3A3B, AHEAD, and OPTIME-CHF) and derived a new PRS to predict the short-term prognosis in ADHF.

Methods: A total of 4550 patients from the Heb-ADHF registry in China were randomly divided into the derivation and validation cohorts (3:2).

Improving effects of eplerenone on atrial remodeling induced by chronic intermittent hypoxia in rats.

Objective: Atrial fibrillation (AF) is closely associated with the overactivation of the renin-angiotensin-aldosterone system. Large cohort studies and recent meta-analyses have shown that the utilization of mineralocorticoid receptor antagonists has positive effects on the prevention and development of AF. This study aimed to investigate the effects of eplerenone on atrial remodeling in AF model rats and elucidate its intrinsic mechanism.

Ameliorative Impact of Liraglutide on Chronic Intermittent Hypoxia-Induced Atrial Remodeling.

Atrial fibrillation (AF) is the most frequent form of clinical cardiac arrhythmias. Previous evidence proved that atrial anatomical remodeling (AAR) and atrial electrical remodeling (AER) are crucial for the progression and maintenance of AF. This study is aimed at investigating the impact of the glucagon-like peptide-1 (GLP-1) receptor agonist, Liraglutide (Lir), on atrial remodeling (AR) mouse model induced by chronic intermittent hypoxia (CIH).

Colloidal Cd Zn S nanocrystals as efficient photocatalysts for H production under visible-light irradiation.

Cd Zn S nanocrystals with sizes ranging from 3-11 nm were synthesized by a simple organic solution method. The nanocrystals possess a cubic zinc-blende structure and the bandgap blue-shifts from 2.1 eV to 3.

Non‑coding RNAs and ovarian diseases (Review).

Non-coding RNAs (ncRNAs) are a diverse family of untranslated transcripts, which serve important roles in numerous biological processes. ncRNAs are emerging as major mediators of gene expression with crucial regulatory functions. Ovarian diseases have a wide variety of clinical pathological types, which have serious impacts on women's health.

Differential Expression of microRNAs in the Ovaries from Letrozole-Induced Rat Model of Polycystic Ovary Syndrome.

Polycystic ovary syndrome (PCOS) is a complex and heterogeneous endocrine disorder. To understand the pathogenesis of PCOS, we established rat models of PCOS induced by letrozole and employed deep sequencing to screen the differential expression of microRNAs (miRNAs) in PCOS rats and control rats. We observed vaginal smear and detected ovarian pathological alteration and hormone level changes in PCOS rats.

[Hadamard transform spectrometer mixed pixels' unmixing method].

Hadamard transform imaging spectrometer is a multi-channel digital transform spectrometer detection technology, this paper based on digital micromirror array device (DMD) of the Hadamard transform spectrometer working principle and instrument structure, obtained by the imaging sensor mixed pixel were analyzed, theory derived the solution of pixel aliasing hybrid method, simulation results show that the method is simple and effective to improve the accuracy of mixed pixel spectrum more than 10% recovery.