Triboelectric tactile sensor for pressure and temperature sensing in high-temperature applications.

Skin-like sensors capable of detecting multiple stimuli simultaneously have great potential in cutting-edge human-machine interaction. However, realizing multimodal tactile recognition beyond human tactile perception still faces significant challenges. Here, an extreme environments-adaptive multimodal triboelectric sensor was developed, capable of detecting pressure/temperatures beyond the range of human perception.

Lightweight and Mechanically Robust Cellulosic Triboelectric Materials for Wearable Self-Powered Rehabilitation Training.

Lightweight and robust self-powered wearable devices are of great importance in rehabilitation and medical assistance, but this places greater demands on the development of functional materials. In particular, a balance between reducing the weight of materials and enhancing their mechanical performance is urgently needed. Here, this study reports a design strategy based on a cross-scale strengthening mechanism, which endows triboelectric materials with mechanically robust properties, and can withstand more than 16,600 times its weight without any deformation.

The synthetic cannabinoid 5F-ADB induced developmental toxicity in Daphnia magna through disrupting the oxidative stress system and the nervous conduction system.

Methyl 2-{[1-(5-fluoropentyl)-1H-indazole-3-carbonyl]amino}-3,3-dimethylbutanoate (5F-ADB), which is classified as an illicit drug in China and most European countries, is susceptible to abuse. The abuse of 5F-ADB must avoid entering the water environment. However, the aquatic toxic effects of 5F-ADB remain unclear.

Highly sensitive electrochemical sensor for lead ions based on Bi-MOF/conducting polymer composites.

Herein, conductive polyaniline (PANI) was chemically polymerized on the surface of a bismuth-based metal-organic framework (Bi-MOF) to form conductive PANI@Bi-MOF composites. FT-IR and PXRD measurements verified the successful production of PANI@Bi-MOF, whereas SEM, TEM, and EDAX mapping demonstrated that PANI was uniformly coated on the surface of Bi-MOF. The resulting PANI@Bi-MOF composites were characterized by cyclic voltammetry (CV and electrochemical impedance spectroscopy (EIS), then used to develop a sensitive electrochemical sensor for the detection of lead ions based on differential pulse anodic stripping voltammetry (DPASV).

CHD6 eviction of promoter nucleosomes maintains housekeeping transcriptional program in prostate cancer.

CHD6, a member of the chromodomain helicase DNA-binding protein family, has been implicated in various diseases and tumors. However, its precise binding model of CHD6 on regulatory functional genes remains poorly understood. In this study, we discovered sharp peaks of CHD6, as the first member of CHD family for housekeeping process, binding only to the promoter region of genes in the C4-2 cell line.

Mechanically Robust Triboelectric Aerogels Enabled by Dense Bridging of MXene.

Aerogels are widely applied for construction, aerospace, military, and energy owing to their lightweight, high specific surface area, and high porosity. The high porosity of aerogels often leads to a lack of mechanical strength, which limits their applications. Here, this study reports a mechanically robust MXene/cellulose nanocrystal composite aerogel enabled by inducing dense bridging through salting-out.

Interface Engineering of RuO/Ni-CoO Heterostructures for enhanced acidic oxygen evolution reaction.

RuO has been recognized as a standard electrocatalyst for acidic oxygen evolution reaction (OER). Nonetheless, its high cost and limited durability are still ongoing challenges. Herein, a RuO/Ni-CoO heterostructure confining a heterointerface (between RuO and Ni-doped CoO) is constructed to realize enhanced OER performance.

Combination Using Magnetic Iron Oxide Nanoparticles and Magnetic Field for Cancer Therapy.

Iron oxide nanoparticles (MNPs) demonstrate notable benefits in magnetic induction, attributed to their distinctive physical and chemical attributes. Emerging cancer treatment utilizing magnetic fields have also gathered increasing attention in the biomedical field. However, the defects of difficult dispersion and poor biocompatibility of MNPs seriously hinder their application.

Probing Different Lengths of the Tertiary Amine Head Group on Triglyceride-Mimetic Ionizable Lipid-Mediated siRNA Delivery.

Lipid nanoparticles (LNPs) have been utilized to deliver small interfering RNA (siRNA) to treat acute liver injury. However, LNPs exhibit suboptimal lysosomal escape capabilities and biodegradability. To address these limitations, we have designed triglyceride-mimetic ionizable lipids by conjugating ,-dimethyl tertiary amine head groups to the sn-2 position of triglyceride (TG) through ester bonds.

Development of a Nomogram Based on Transcriptional Signatures, IFN-γ Response and Neutrophils for Diagnosis of Tuberculosis.

Purpose: Tuberculosis (TB) is a major global health threat and its diagnosis remains challenging. This study aimed to develop a nomogram that incorporated peripheral blood transcriptional signatures and other blood tests for the diagnosis of tuberculosis.

Patients And Methods: Patients with TB, patients with other definite pulmonary diseases (OPD), individuals with latent tuberculosis infection (LTBI), and healthy controls (HC) were retrospectively enrolled between May 2017 and April 2018.

Strong and Stable Woody Triboelectric Materials Enabled by Biphase Blocking.

Driven by the "Internet of Everything" (IoE) vision, the demand for smart materials is growing. Wood, one of the most abundant and renewable resources, has long been a staple in construction and furnishing applications. To further expand its application range, this study developed a high-strength, stable wood-based triboelectric material through a synergistic biphasic mechanism.

Deformable dose prediction network based on hybrid 2D and 3D convolution for nasopharyngeal carcinoma radiotherapy.

Radiotherapy is recognized as the primary treatment for nasopharyngeal carcinoma (NPC). Rapid and accurate dose prediction is crucial for enhancing the quality and efficiency of radiotherapy planning. However, the current dose prediction model based on 2D architecture cannot effectively learn the spatial information among slices.

N-doped CoO-anchored ultrafine Pt nanoparticles for acidic hydrogen evolution reaction.

An efficient hydrogen evolution reaction catalyst of ultrafine Pt nanoparticles loaded onto N-doped CoO was synthesized. This catalyst displayed high electrocatalytic activity and stability. The outstanding performance is attributed to the interactions between the active sites and support, as well as the regulation of the electronic structure through covalent nitrogen bridging.

Alizarin attenuates oxidative stress-induced mitochondrial damage in vascular dementia rats by promoting TRPM2 ubiquitination and proteasomal degradation via Smurf2.

Background: Alizarin (AZ) is a natural anthraquinone with anti-inflammatory and moderate antioxidant properties.

Purpose: In this study, we characterized the role of AZ in a rat model of vascular dementia (VaD) and explored its underlying mechanisms.

Methods: VaD was induced by bilateral common carotid artery occlusion.

Graded Nanotexturing Architectural Wearable Triboelectric Sensor for Programmable Haptic Exploration.

Emulating biological perception mechanisms to construct intelligent sensing devices and systems represents a paradigm for promoting human-computer interaction in the Internet of Everything era. Nonetheless, developing highly sensitive, real-time sensing and rapidly integrated intelligent interaction units remains a challenging and time-consuming endeavor. This study employs a low-temperature glow discharge technique to rapidly fabricate graded nanotexturing architectural triboelectric nanopaper, upon which wearable triboelectric sensors for real-time tactile detection are designed.

Impact of contrast-enhanced CT in the dosimetry of SBRT for liver metastases treated with MR-Linac.

Background: To investigate the impact of using contrast-enhanced computed tomography (CHCT) in the dosimetry of stereotactic body radiation therapy (SBRT) for liver metastases treated with MR-Linac.

Methods: A retrospective study was conducted on 21 liver cancer patients treated with SBRT (50 Gy in 5 fractions) using a 1.5 Tesla Unity MR-Linac.

Hemodynamics study of anterior cerebral artery with different sac centerline lengths for rupture risk assessment.

The present research extensively investigates the significance of the sac centerline length of the anterior cerebral artery (ACA) on aneurysm rupture risk. Hemodynamic factors influencing aneurysm rupture are assessed to identify critical regions prone to rupture. Wall shear stress is analyzed by modeling blood flow in three real saccular ACA cases with varying sac centerline lengths.

Rational Design of Triboelectric Materials and Devices for Self-Powered Food Sensing.

Against the backdrop of rapid advancements in 5G and Internet of Things (IoT) technologies, there is an urgent need to upgrade food sensing systems to achieve automation, digitalization, and intelligence. However, this transformation process faces numerous challenges. Triboelectric nanogenerators (TENGs), as an emerging energy conversion and sensing technology, play a crucial role in this context.

Triboelectrically Empowered Biomimetic Heterogeneous Wettability Surface for Efficient Fog Collection.

Biomimetic engineering surfaces featuring heterogeneous wettability are vital for atmospheric water harvesting applications. Existing research predominantly focuses on the coordinated regulation of surface wettability through structural and chemical modifications, often overlooking the prevalent triboelectric charge effect at the liquid-solid interface. In this work, we designed a heterogeneous wettability surface by strategic masking and activated its latent triboelectric charge using triboelectric brushes, thereby enhancing the removal and renewal of surface droplets.

The Tribological Properties of Novel Sulfoximine Derivatives as Lubricant Additives.

Introducing an additive is a practical approach to improve the lubrication performance of base oil in the field of tribology. Herein, a series of sulfoximine derivatives was synthesized and incorporated into base oil A51 as additives. The tribological properties of these lubricants were evaluated at both room and high temperatures, and the result demonstrated that they displayed excellent friction reduction and wear resistance in the friction process under both test conditions.