The triglyceride-glucose index and its obesity-related derivatives as predictors of all-cause and cardiovascular mortality in hypertensive patients: insights from NHANES data with machine learning analysis.

Background: Hypertension (HTN) is a global public health concern and a major risk factor for cardiovascular disease (CVD) and mortality. Insulin resistance (IR) plays a crucial role in HTN-related metabolic dysfunction, but its assessment remains challenging. The triglyceride-glucose (TyG) index and its derivatives (TyG-BMI, TyG-WC, and TyG-WHtR) have emerged as reliable IR markers.

The prediction value of serum anion gap for short-term mortality in pulmonary hypertension patients with sepsis: a retrospective cohort study.

Background: The relationship between anion gap (AG) and short-term mortality of pulmonary hypertension (PH) patients with sepsis in the intensive care unit (ICU) remains unclear.

Methods: This study involved a retrospective analysis of incident PH patients with sepsis first admitted to the ICU in the MIMIC IV database (2008 to 2019). Short-term outcomes include in-hospital mortality and 28-day mortality.

Comparison of two-year myopia control efficacy between spectacle lenses with highly aspherical lenslets and orthokeratology lenses.

Purpose: To compare the two-year efficacy of spectacle lenses with highly aspherical lenslets (HAL) and orthokeratology (OK) lenses in managing myopia in children.

Methods: This retrospective study examined medical records from the Affiliated Eye Hospital of Wenzhou Medical University, involving 1683 HAL users and 1192 OK users. Participants were children aged 8-13 with a refractive error of -0.

Efficacy and safety of Shexiang Baoxin Pill (MUSKARDIA) in patients with stable coronary artery disease across different weight subgroups.

Ethnopharmacological Relevance: Shexiang Baoxin Pill (MUSKARDIA), a traditional Chinese patent medicine, plays a crucial role in both preventing and treating diverse cardiovascular diseases, including coronary heart disease, myocardial infarction (MI), and heart failure. Preclinical research has demonstrated that the cardioprotective effects of MUSKARDIA are achieved through multiple pathways, such as enhancing coronary artery dilation, fostering new blood vessel growth, reducing inflammation and oxidative stress, improving lipid metabolism, and protecting vascular endothelium.

Aim Of The Study: This subgroup analysis aimed to evaluate the efficacy and safety of Shexiang Baoxin Pill (MUSKARDIA) plus optimal medical therapy (OMT) across different weight categories in treating stable coronary artery disease (CAD).

Lipoprotein(a) and Atrial Fibrillation: Mechanistic Insights and Therapeutic Approaches.

Elevated lipoprotein(a) [Lp(a)] levels are increasingly recognized as a significant risk factor for cardiovascular diseases and may also contribute to atrial fibrillation (AF). This review investigated the indirect mechanisms through which Lp(a) may influence AF, including proatherogenic, prothrombotic, and proinflammatory pathways. Traditional lipid-lowering therapies, such as lifestyle modifications and statins, have limited effects on Lp(a) levels.

Comparison of Catheter Ablation in Patients with Paroxysmal Non-valvular Atrial Fibrillation and Heart Failure with Preserved Ejection Fraction.

The efficacy of radiofrequency ablation (RFA) in patients with atrial fibrillation (AF) and heart failure with preserved ejection fraction (HFpEF) has been established, but the efficacy and safety of cryoballoon ablation (CBA) and pulsed field ablation (PFA) remain unclear. This retrospective cohort study included 223 patients with paroxysmal non-valvular AF and HFpEF who underwent their first AF ablation between January 2017 and December 2021 and were divided into RFA (n = 77), CBA (n = 127), and PFA (n = 19) groups. After a mean follow-up of 11.

Enhanced particle swarm optimization with chaotic search for offshore micro-energy systems.

As the global energy landscape shifts and sustainability becomes crucial, the offshore oil and gas sector confronts significant challenges and opportunities. This paper addresses the issues of energy efficiency and environmental impact of optimizing offshore micro-energy systems (OMIES) by proposing a multi-objective optimization model that integrates chaotic local search and particle swarm optimization (PSO). The model aims to achieve optimal scheduling of the energy system by comprehensively considering operational costs, carbon emissions, energy utilization efficiency, and energy fluctuation risks.

Two-dimensional identification of lower limb gait features based on the variational modal decomposition of sEMG signal and convolutional neural network.

Background: Gait feature recognition is crucial to improve the efficiency and coordination of exoskeleton assistance. The recognition methods based on surface electromyographic (sEMG) signals are popular. However, the recognition accuracy of these methods is poor due to ignoring the correlation of the time series of sEMG signals.

Association between the systemic immunity-inflammation index and stroke: a population-based study from NHANES (2015-2020).

Background The systemic immunity-inflammation index(SII) is a new indicator of composite inflammatory response. Inflammatory response is an important pathological process in stroke. Therefore, this study sought to investigate the association between SII and stroke.

Multifunctional Optimization of MXene for Enhanced Comprehensive Performance of Crystal Silicon-MXene Back-Heterojunction Solar Cells.

Enhancing the cost-performance ratio is a fundamental objective for the advancement of the photovoltaic sector. In this context, the development of innovative solar cells that offer a straightforward device configuration but high performance is arguably the most crucial element. Herein, an undoped back-heterojunction crystalline silicon (c-Si) solar cell is endeavored to be crafted by simply drop-casting a TiCT MXene ethanol colloidal solution onto the backside of an n-type c-Si (n-Si) wafer.

In Situ Modulation of NiFeOOH Coordination Environment for Enhanced Electrocatalytic-Conversion of Glucose and Energy-Efficient Hydrogen Production.

Glucose electrocatalytic-conversion reaction (GCR) is a promising anode reaction to replace the slow oxygen evolution reaction (OER), thus promoting the development of hydrogen production by electrochemical water splitting. Herein, NiFe-based metal-organic framework (MOF) is used as a precursor to prepare W-doped nickel-iron phosphide (W-NiFeP) nanosheet arrays by ion exchange and phosphorylation, which exhibit a high electrocatalytic activity toward the hydrogen evolution reaction (HER), featuring an overpotential of only -179 mV to achieve the current density of 100 mA cm in alkaline media. Notably, electrochemical activation of W-NiFeP facilitates the in situ formation of phosphate groups producing W,P-NiFeOOH, which, in conjunction with the W co-doped amorphous layers, leads to a high electrocatalytic performance toward GCR, due to enhanced proton transfer and adsorption of reaction intermediates, as confirmed in experimental and theoretical studies.

[Pollution Characteristics and Risk Assessment of Microplastics in the Xiamen Houxi River Watershed].

Microplastics, defined as minuscule plastic particles measuring less than five millimeters （5 mm） in size, have become pervasive in various environments. Watershed areas, perpetually subjected to escalating human activities, face a growing and persistent threat from microplastic pollution. This study aimed to investigate the characteristics and ecological risk posed by microplastic pollution in the Houxi River watershed of Xiamen.

Pralatrexate represses the resistance of HCC cells to molecular targeted agents via the miRNA-34a/Notch pathway.

Metabolism-related pathways are important targets for intervention in the treatment of hepatocellular carcinoma (HCC), but few studies have reported on the combination of inhibitors of folate metabolism-related enzymes and molecularly targeted drugs for HCC. The results of the present work are the first to reveal the effects of an inhibitor of dihydrofolate reductase (DHFR), pralatrexate, on the sensitivity of HCC cells to molecularly targeted agents examined using multiple assays. In HCC cells, knockdown of DHFR or treatment with pralatrexate enhanced the sensitivity of HCC cells to molecularly targeted agents, such as sorafenib, regorafenib, lenvatinib, cabozantinib, or anlotinib.

Stabilization and Surface Functionalization of Palladium Disulfide Nanoparticles with Acetylene Derivatives.

Metal chalcogenide nanoparticles have been attracting extensive attention in diverse fields. Traditionally these nanoparticles are stabilized by organic ligands such as thiols and amines involving nonconjugated core-ligand interfacial interactions. In the present study, a facile wet-chemistry method is described for the synthesis of palladium disulfide (PdS) nanoparticles capped with acetylene derivatives.

Applications of Digital Enzyme-Linked Immunosorbent Assays in Ophthalmology.

Digital enzyme-linked immunosorbent assays (dELISAs) very sensitively detect biomarkers that cannot be measured using traditional methods. The molecules are confined within a small volume, their counts accurately computed, and the results rapidly delivered. Digital ELISAs find many applications.

Visuomotor Navigation for Embodied Robots With Spatial Memory and Semantic Reasoning Cognition.

The fundamental prerequisite for embodied agents to make intelligent decisions lies in autonomous cognition. Typically, agents optimize decision-making by leveraging extensive spatiotemporal information from episodic memory. Concurrently, they utilize long-term experience for task reasoning and foster conscious behavioral tendencies.

Integrating Neural Radiance Fields End-to-End for Cognitive Visuomotor Navigation.

We propose an end-to-end visuomotor navigation framework that leverages Neural Radiance Fields (NeRF) for spatial cognition. To the best of our knowledge, this is the first effort to integrate such implicit spatial representation with embodied policy end-to-end for cognitive decision-making. Consequently, our system does not necessitate modularized designs nor transformations into explicit scene representations for downstream control.

Female urinary incontinence in China after 15 years' efforts: Results from large-scale nationwide surveys.

Urinary incontinence (UI) is a disease that quietly yet seriously impacts women's health and represents a global health burden that is often neglected. This study aims to systematically assess the prevalence and dynamics of female UI in China, and can inform further policies and have international implications. This study used three nationwide investigations: A national cross-sectional survey in 2021; another nationwide cross-sectional survey in 2006; and data regarding the institutions and physicians providing pelvic floor rehabilitation services from 2005 to 2019.

UV-OZONE Treatment for Suppressing Surface Damages on Silicon Solar Cells.

In the preparation process of c-Si solar cells, qualified Si wafers must be processed through mechanical processing during manufacturing. Most of these processes involve mechanical processing, which inevitably results in severe mechanical damage layers and a wafer surface with large roughness. The current industry practice involves etching of the damage layer using an acid/alkali solution, and it is usually followed by deposition of additional passivation layers in the subsequent processes.

Identification and Verification of the Oxidative Stress-Related Signature Markers for Intracranial Aneurysm-Applied Bioinformatics.

Background: Intracranial aneurysm (IA) is a localized abnormal dilation of the cerebral vascular wall, the degeneration of which is closely related to high oxidative stress.

Methods: Clinical information and RNA-seq data from five public datasets were downloaded from the Gene Expression Omnibus (GEO). Using the "GSVA" package, enrichment analysis was performed on the gene sets of the oxidative stress, reactive oxygen species (ROS), metabolism, and inflammatory pathways retrieved from the MsigDB and Kyoto encyclopedia of genes and genomes (KEGG) databases.

Spectacle correction may affect refractive progression in children with unilateral myopic anisometropia: A retrospective study.

Objective: To investigate the effect of spectacle correction on refractive progression in children with unilateral myopic anisometropia (UMA).

Methods: In this retrospective study, 153 children with UMA (aged 8-12 years) were recruited and classified into an uncorrected (UC) group (n = 47) and a spectacle (SP) group (n = 106). The spherical equivalent refraction (SER) of the myopic eyes ranged from -0.