Serum biochemical indicators of hepatobiliary function in dogs following prolonged anaesthesia with sevoflurane or isoflurane.

Objective: To investigate the changes in serum enzymes considered as biochemical indicators of hepatobiliary function in dogs following 5 hours of anaesthesia with isoflurane (ISO) or sevoflurane (SEVO).

Study Design: Experimental randomized crossover study, with intervals of at least 15 days between successive treatments.

Animals: Eight healthy adult mongrel dogs, four male, four female, weight 13.

Genetic influence on baroreflex sensitivity in normotensive young men.

Background: The dysfunction of baroreflex plays an important role in the pathogenesis of essential hypertension. Recent studies suggest that approximately 40% of the variation in baroreflex sensitivity (BRS) may be accounted for by genetic factors. However, only a few such genetic polymorphisms have been explicitly identified.