Publications by authors named "Liu Changwei"

Objective: To evaluate the role of multidetector row spiral computed tomography in the diagnosis of popliteal artery entrapment syndrome (PAES).

Method: Ten patients (13 limbs) were diagnosed as PAES through open surgery in Peking Union Medical College Hospital from January 2006 to December 2009, among whom three (30.0%) had both limbs involved.

View Article and Find Full Text PDF

Ceftriaxone-induced immune haemolytic anemia is rare but severe complication of this type of antibiotics. In this article, we present a 43-year old patient who suffered from ceftriaxone-induced haemolysis complicated with acute portal vein thrombosis. After successful salvage and transfusion, we underwent thrombolysis via superior mesenteric artery route.

View Article and Find Full Text PDF

Objective: To evaluate the application of carotid endarterectomy (CEA) in the treatment of patients with bilateral moderate to severe carotid stenosis.

Methods: We retrospectively analyzed the clinical data of 82 patients with bilateral moderate to severe carotid stenosis who were admitted to our hospital from January 2006 to December 2009. Of these patients, 64 underwent ipsilateral CEA and 18 underwent bilateral CEA.

View Article and Find Full Text PDF

Objective: To summarize the incidence, diagnosis and treatment of acute coronary syndrome (ACS) after carotid endarterectomy (CEA).

Methods: From 2003 to 2009, 159 CEA were performed in 143 cases with severe atherosclerotic carotid artery stenosis. The clinical datas of ACS after CEA were collected.

View Article and Find Full Text PDF

Objective: To explore whether 125I-vascular endothelial growth factor (VEGF)-coated artificial vascular patch accelerate the vessel endothelialization and inhibit thrombosis.

Methods: Ten adult male New Zealand rabbits (weighing 2.5-3.

View Article and Find Full Text PDF

It has been demonstrated that many flavonoids possess a potent and broad spectrum of antitumor activity. Liquiritigenin is a flavanone extracted from Glycyrrhizae. This study investigated the effects of liquiritigenin on cell viability and apoptosis induction in human cervical carcinoma (HeLa) cells.

View Article and Find Full Text PDF

Objective: To investigate surgical procedures for popliteal artery occlusive disease.

Methods: The clinical data of 25 patients with popliteal artery occlusive disease from June 2007 to June 2008 was analyzed retrospectively. There were 18 male and 7 female with an average age of (53 ± 21) years.

View Article and Find Full Text PDF

Objective: To assess the patency and complications of the polytetrafluoroethylene (PTFE) graft for hemodialysis access and to summarize the experiences in the treatment of graft occlusions.

Methods: The clinical data of 30 patients who underwent forearm PTFE graft for hemodialysis access from March 2003 to December 2008 in our hospital were retrospectively analyzed.

Results: Patients were followed up for (28.

View Article and Find Full Text PDF

Our case of primary leiomyosarcomas involved retrohepatic, suprarenal, and infrarenal inferior vena cava (IVC). Preoperative phlebography proved that there was adequate collateral circulation formed, which allowed us to achieve en bloc resection including segment I and II IVC without either extracorporeal circulation or prosthetic revascularization of the IVC and renal vessels. Our choice of en bloc resection including segment I and II IVC without extracorporeal circulation or prosthetic replacement of the vessels was justified as the patient had normal liver and kidney function after the operation.

View Article and Find Full Text PDF

We report a ruptured venous aneurysm, an unusual complication of venous arterialization for lower limb ischemia in Buerger's disease. Arteriovenous shunt ligation and aneurysm resection were performed successfully, with the distal limb perfusion preserved. By our very limited experience, venous arterialization may be ineffective on improving lower limb ischemia with Buerger's disease.

View Article and Find Full Text PDF

Objective: To summarize advancement of diagnosis and surgical intervention of popliteal artery entrapment syndrome (PAES).

Methods: From March 2006 to August 2009, 11 patients (14 limbs) underwent surgical procedures, including 9 males (81.8%), with a median age of 22 years old (arranged from 15 to 56 years old).

View Article and Find Full Text PDF

Objective: To analyze the outcome and risk factors of endovascular revascularization of lower limb artery for elder patients.

Methods: From January 2006 to November 2008, 86 elder patients (98 ischemia limbs) underwent endovascular revascularization due to lower limb ischemia. Age of this group were 60 to 82 years old with a mean of (70 +/- 6) years old.

View Article and Find Full Text PDF

Objective: To evaluate the efficacy of infrapopliteal angioplasty as the first-choice procedure in patients with critical lower limb ischemia.

Methods: From December 2005 to May 2009, infrapopliteal angioplasty was considered as the first-choice method in consecutive patients with infrapopliteal occlusive disease hospitalized for critical ischemia. Fifty-four patients (61 limbs) with a mean age of 66 years old (37 male and 17 female) underwent infrapopliteal balloon angioplasty.

View Article and Find Full Text PDF

Objective: To find out the distribution of emergent cases of elderly in vascular surgery and to evaluate the complications in peri-operation.

Methods: We retrospectively analyzed all the vascular emergency operations over 60 years old from Jan. 2006 to Oct.

View Article and Find Full Text PDF

Objective: To analyze the etiology, characteristics, and treatment outcomes of peripheral arterial disease (PAD) in patients under 45 years old.

Methods: One hundred and ninety-three cases under 45 years old with PAD were included from January 1999 to January 2009. The demography, etiology, surgical data, treatment outcomes of these patients were evaluated and analyzed.

View Article and Find Full Text PDF

Objective: To investigate the role of pulse wave velocity on he predication and diagnosis for peripheral artery diseases among diabetic patients.

Methods: Ankle-brachial index (ABI) and brachial-ankle pulse wave velocity (baPWV) were detected simultaneously in 1500 type 2 diabetic patients which over 50 years old with one or more risk factors.

Results: baPWV speeded up in enrolled diabetic patients when ABI showed normal; and more faster in female patients compared with males (male vs.

View Article and Find Full Text PDF

Lysine 48-linked polyubiquitin chains usually target proteins for 26 S proteasomal degradation; however, this modification is not a warrant for destruction. Here, we found that efficient degradation of a physiological substrate UbcH10 requires not only an exogenous polyubiquitin chain modification but also its unstructured N-terminal region. Interestingly, the unstructured N-terminal region of UbcH10 directly binds the 19 S regulatory complex of the 26 S proteasome, and it mediates the initiation of substrate translocation.

View Article and Find Full Text PDF

The role of Lys-63 ubiquitin chains in targeting proteins for proteasomal degradation is still obscure. We systematically compared proteasomal processing of Lys-63 ubiquitin chains with that of the canonical proteolytic signal, Lys-48 ubiquitin chains. Quantitative mass spectrometric analysis of ubiquitin chains in HeLa cells determines that the levels of Lys-63 ubiquitin chains are insensitive to short-time proteasome inhibition.

View Article and Find Full Text PDF

Objective: To investigate the role of vascular endothelial growth factor-activating transcriptional factor (VEGF-ATF) on the VEGF signaling pathway in diabetes mellitus.

Methods: Totally, 20 C57BL/6 mice fed with high fat diet was induced into diabetes mellitus. Ten diabetes mellitus mice received a lower limb muscle injection with VEGF-ATF plasmid, and another ten were as control.

View Article and Find Full Text PDF

Objective: To investigate the clinical characteristics and treatment strategy of lower extremity arterial occlusive disease in patients with Crohn's disease (CD).

Methods: Clinical information of 9 cases suffering from lower extremity arterial occlusion and CD was investigated retrospectively.

Results: All the cases were less than 50 years old and the most were females (8/9).

View Article and Find Full Text PDF

Objective: This study evaluated the feasibility, efficacy, and outcome of endovascular therapy combined with immunosuppressive therapy for aortic pseudoaneurysms in patients with Behçet disease.

Methods: Between April 2002 and April 2008, 12 pseudoaneurysms (9 involving the intrarenal abdominal aorta, 1 at the suprarenal level, and 2 in the supraceliac aorta) in nine men and one woman with Behçet disease were evaluated at Peking Union Medical Center (PUMC). Three bifurcated stent grafts and seven tubular stent grafts, including two fenestrated stent grafts, were deployed.

View Article and Find Full Text PDF

Objective: To evaluate the early and midterm outcomes of carotid endarterectomy (CEA) compared with carotid stenting (CAS) in patients with carotid artery stenosis.

Methods: A prospective randomized single-center clinical trail to compare with endarterectomy and stenting in patients with symptomatic carotid stenosis of at least 50% and asymptomatic stenosis of at least 70%. From May 2004 to December 2006, there were 40 patients who agreed with the treatment were randomly assigned to undergo either CEA or CAS.

View Article and Find Full Text PDF

Background: Intravenous leiomyomatosis (IVL) is a rare tumor that is histologically benign but biologically malignant. Less than 200 cases of IVL have been reported, most of them were individual reports.

Methods: Six patients with IVL involving the inferior vena cava were analyzed.

View Article and Find Full Text PDF

Objective: To conclude clinical character and treatment strategy of lower extremity arterial occlusive disease with Crohn's disease.

Method: A female patient suffering lower extremity arterial occlusion and Crohn's disease was admitted to Peking Union Medical College Hospital in 2007. The other 8 similar cases with clinical details were found through a comprehensive literature search from 1966 to 2007.

View Article and Find Full Text PDF
Article Synopsis
  • Myoglobin, found in skeletal muscles, may negatively affect the body’s ability to create new blood vessels during ischemia, leading to worsened recovery.
  • Transgenic mice engineered to overexpress myoglobin (MbTG) showed significantly poorer blood flow recovery and higher muscle tissue necrosis compared to normal mice (WT) in a study involving femoral artery ligation.
  • The study results indicate that increased myoglobin levels correlate with reduced vascular density and impaired angiogenic response, ultimately leading to less effective healing in ischemic muscles.
View Article and Find Full Text PDF