Publications by authors named "Liu Ailing"

The search for new anode materials with high lithium-ion battery (LIB) capacity has attracted considerable attention due to the increasing need for electrical power. Here, we utilized first-principles calculations to develop a honeycomb-structured BCN monolayer, which exhibits an ultra-high Li-ion storage capacity of 2244 mA h g as an anode material for LIBs. Furthermore, the calculations show that the BCN monolayer has a comparatively small diffusion barrier of 0.

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Objective: To improve the accuracy of food intelligent recognition and weight estimation technology, establish a large-scale food image dataset.

Methods: Building large-scale food image and ingredient datasets based on web crawler technology, professional manual collection, and regular user uploads.

Results: A big dataset was constructed containing over 1.

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The Arabidopsis tandem CCCH zinc finger 1 (TZF1) is an RNA-binding protein that plays a pivotal role in plant growth and stress response. In this report, we show that TZF1 contains two intrinsically disordered regions necessary for its localization to stress granules (SGs). TZF1 recruits mitogen-activated protein kinase (MAPK) signaling components and an E3 ubiquitin ligase KEEP-ON-GOING (KEG) to SGs.

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Background: The efficacy of ustekinumab (UST) and infliximab (IFX) in Crohn's disease (CD) patients with intestinal stenosis remains uncertain.

Objective: This study aims to compare the efficacy of UST and IFX in the treatment of CD patients with intestinal stenosis.

Design: This was a retrospective and multicenter cohort study.

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Article Synopsis
  • Atopic dermatitis (AD) is the most burdensome skin disease in China, and this study examines its prevalence from 1990 to 2021, highlighting trends based on age and sex differences.
  • The analysis shows a slight overall decrease in the age-standardized prevalence rate (ASPR), but the rates remain higher among females and young children, with projections indicating increased future prevalence, especially in the under-5 and 5-9 age groups.
  • The study concludes that healthcare providers need to enhance education and management strategies to address the rising burden of AD, particularly among children and females in China.
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Green tea possesses a range of beneficial effects, including anti-obesity, antioxidant, and anti-inflammatory properties, owing to its biologically active components, primarily catechins such as epicatechin (EC), epicatechin gallate (ECG), epigallocatechin (EGC), and epigallocatechin gallate (EGCG). However, few studies have investigated the four catechin monomers simultaneously, and the molecular mechanisms of their anti-obesity effects have not been fully elucidated. In this study, we investigated the effects of four catechin monomers on the differentiation of 3T3-L1 preadipocytes of mice.

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Rationale: The interstitial pneumonia (IP) linked to vedolizumab (VDZ) in patients with ulcerative colitis (UC) is rare. Prompt diagnosis and treatment can improve patient outcomes.

Patient Concerns: A 39-year-old man with UC who received VDZ as sole therapy developed symptoms such as chest tightness, cough, and suffocation.

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Article Synopsis
  • Vedolizumab (VDZ) is an antibody treatment for moderate-to-severe ulcerative colitis (UC) and this study evaluated its real-world effectiveness and safety in Northern China from March 2021 to November 2022.
  • Among 73 patients, the clinical response rates improved significantly over time, with 69.9% at week 14 and 90.5% at week 52; however, only a small percentage achieved mucosal healing.
  • About 23.3% of patients experienced mild adverse events, and factors like higher disease severity scores and low hemoglobin levels at the start were linked to a greater chance of losing response to the treatment (LOR) after initial therapy.
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Sustainable development has become an inevitable trend in the world's green chemical industry for a generation or more. In this study, a monodisperse magnetic polystyrene mesoporous composite microsphere (MPPS) composed of FeO nanoparticles loaded on polystyrene mesoporous microspheres is introduced. These microspheres serve as effective adsorbents for the swift removal of cationic dyes.

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Objective: To analyze the clinical features and genetic basis of a child with Disorder of sex development (DSD).

Methods: A child who was admitted to the Linyi People's Hospital for primary amenorrhoea on July 29, 2019 was selected as the study subject. Clinical data of the child was collected.

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Lung cancer is a leading cause of cancer deaths and imposes an enormous economic burden on patients. It is important to develop an accurate risk assessment model to determine the appropriate treatment for patients after an initial lung cancer diagnosis. The Cox proportional hazards model is mainly employed in survival analysis.

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Background: Endoscopic evaluation in diagnosing and managing ulcerative colitis (UC) is becoming increasingly important. Several endoscopic scoring systems have been established, including the Ulcerative Colitis Endoscopic Index of Severity (UCEIS) score and Mayo Endoscopic Subscore (MES). Furthermore, the Toronto Inflammatory Bowel Disease Global Endoscopic Reporting (TIGER) score for UC has recently been proposed; however, its clinical value remains unclear.

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Article Synopsis
  • Despite lung cancer screening guidelines emphasizing the need for low-dose computed tomography (LDCT), actual participation among high-risk individuals remains low, and its effectiveness in reducing lung cancer mortality is not well-documented.
  • The objective of the study was to assess the impact of opportunistic LDCT screening on prognosis in lung cancer patients in mainland China, examining data from a cohort diagnosed at Weihai Municipal Hospital between 2016 and 2021.
  • The study analyzed a sample of 5,234 patients, comparing outcomes for those diagnosed through opportunistic screening against those who were not, and used advanced statistical methods to control for potential biases in the findings.
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Alcoholic liver disease (ALD) remains a major cause of liver-related morbidity and mortality worldwide. Tea polyphenols (TPs) possess strong antioxidant activity; cassia seed extract (CSE) has the effect of brightening the eyes; and extract (AGE) has the function of protecting the liver. However, the synergistic hepatoprotective effect of TP, AGE and CSE as a joint formulation is unknown.

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The scoring systems commonly used to assess endoscopic disease severity of ulcerative colitis (UC) in clinical research and practice include the Mayo endoscopic score (MES), ulcerative colitis endoscopic severity index (UCEIS), and degree of ulcerative colitis burden of luminal inflammation (DUBLIN). We aimed to assess and compare the predictive efficacy of the MES, DUBLIN score and UCEIS score for prognosis in UC patients treated with vedolizumab (VDZ). Seventy-four UC patients who treated with VDZ from September 2021 to February 2023 were retrospectively enrolled.

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Background: Chinese urban residents consume more salt from meals prepared outside home than in the past. The purpose of this study is to understand Chinese consumer demand for salt reduction as expressed through their orders on meal delivery apps (MDAs), restaurants' willingness to promote salt reduction, and the extent to which restaurants comply with reduced salt requests.

Methods: We analyzed consumer comments extracted from 718 restaurants on a Chinese MDA called ELEME for orders made in the July-December 2020 timeframe.

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Clathrin-mediated endocytosis (CME), the major cellular entry pathway, starts when clathrin assembles on the plasma membrane into clathrin-coated pits (CCPs). Two populations of CCPs are detected within the same cell: 'productive' CCPs that invaginate and pinch off, forming clathrin-coated vesicles (CCVs) [1, 2], and 'abortive' CCPs [3, 4, 5] that prematurely disassemble. The mechanisms of gating between these two populations and their relations to the functions of dozens of early-acting endocytic accessory proteins (EAPs) [5, 6, 7, 8, 9] have remained elusive.

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Objective: To optimize the detection conditions and evaluate of cystatin C(CysC) by liquid protein microarray.

Methods: CysC was detected by double antibody sandwich method using liquid protein microarray. On the basis of determining the optimal concentration combination of captured antibody and detected antibody, the detection conditions were optimized by determining the biological detection limit and lower detection limit, drawing the S-shaped curve and judging the linear range, and establishing the standard curve and regression equation.

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Boron-carbon clathrates have attracted great attention due to their unique sp-bonded structure and excellent electronic properties. Here, by performing first-principles calculations, we predicted six stoichiometric Na-B-C clathrates (NaBC, NaBC, NaBC, NaBC, NaBC, and NaBC) based on Na-doped boron-carbon clathrates. As a result, NaBC, NaBC, and NaBC were found to become energetically favorable.

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Women aged 18-49 years are women of childbearing age. Their nutrition knowledge (NK) is not only related to their physical health but also affects the diet quality of the entire family and the health status of the next generation. Studies that assess the NK level of women of childbearing age using representative data in China are lacking.

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Extracellular polymeric substances are mainly synthesized via a variety of biosynthetic pathways in bacteria. Bacilli-sourced extracellular polymeric substances, such as exopolysaccharides (EPS) and poly-γ-glutamic acid (γ-PGA), can serve as active ingredients and hydrogels, and have other important industrial applications. However, the functional diversity and widespread applications of these extracellular polymeric substances, are hampered by their low yields and high costs.

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Polyphenol oxidase (PPO) is a metalloenzyme with a type III copper core that is abundant in nature. As one of the most essential enzymes in the tea plant (Camellia sinensis), the further regulation of PPO is critical for enhancing defensive responses, cultivating high-quality germplasm resources of tea plants, and producing tea products that are both functional and sensory qualities. Due to their physiological and pharmacological values, the constituents from the oxidative polymerization of PPO in tea manufacturing may serve as functional foods to prevent and treat chronic non-communicable diseases.

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The existing agricultural insecticides have developed drug resistance from long-term use. Isoxazoline derivatives are new insecticides discovered in the 21st century. Because of their unique insecticidal mechanism, high selectivity, safety, and no significant cross resistance with the existing pesticides on the market, they have become a hot spot in the field of pesticide research.

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