Publications by authors named "Liu Aihua"

Electron-nuclear coupling plays a crucial role in strong laser induced molecular dissociation dynamics. The interplay between electronic and nuclear degrees of freedom determines the pathways and outcomes of molecular fragmentation. However, a full quantum mechanical treatment of electron-nuclear dynamics is computationally intensive.

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Background: There is limited information on the effect of potassium (K) on the taste quality of rice. Field experiments with five K fertilizer application rates (0, 60, 120, 180, and 240 kg KO ha) were conducted in 2019 and 2020 using two cultivars (Xiadao No. 1 and Shenliangyou 5814) to study the effects of K fertilization on grain yield, taste quality, starch components, and protein components in grains.

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Under heavy load conditions, bearings are subjected to non-uniform and frequently changing loads, which leads to randomness in the spatial distribution of bearing degradation characteristics. Aiming at the problem that the traditional degradation index cannot accurately reflect the degradation state of heavy-duty bearings in the whole life cycle, a new degradation evaluation method based on multi-domain features is proposed in this paper, which aims to capture the early degradation point of heavy-duty bearings and characterize their degradation trend. Firstly, the energy entropy feature is obtained by improving the wavelet packet decomposition, and the original multi-domain feature set is constructed by combining the time domain and frequency domain features.

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The gradual rise of CO is one of the global climate changes, Cd stress is also a major abiotic stress factor that affects rice (Oryza sativa L.). The rice seedlings were treated under two CO concentrations and two CdCl concentrations for 7 days (treatments names: 400 ± 20 μmol mol CO and 0 μmol L CdCl concentrations, AC; 400 ± 20 μmol mol CO and 150 μmol L CdCl concentrations, Cd; 800 ± 20 μmol mol CO and 0 μmol L CdCl concentrations, EC; 800 ± 20 μmol mol CO and 150 μmol L CdCl concentrations, EC + Cd).

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Article Synopsis
  • Liposarcoma is a rare malignant tumor that can occur in the mediastinum, and most existing information comes from scattered reports rather than extensive studies.
  • A 51-year-old man presented with respiratory symptoms and was found to have a large mediastinal mass that was misidentified as a teratoma; after surgery, he was diagnosed with dedifferentiated liposarcoma.
  • Despite surgical intervention and chemotherapy, the patient experienced rapid recurrence and ultimately died four months post-surgery, highlighting the need for correct diagnosis and treatment strategies for this aggressive condition.*
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Background: Both Borrelia burgdorferi (Bb) and Anaplasma phagocytophilum (Ap) can infect humans and animals through tick-borne transmission, resulting in zoonosis. Under certain conditions, human infection can lead to Lyme disease (LD) and human granulocytosis (HGA), whereas infection in animals can cause various acute and non-specific symptoms. The combination of Bb and Ap has been reported to increase the disease severity in infected animals.

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This study aims to develop a reliable predictive model for assessing intracranial aneurysm (IA) instability by utilizing four-dimensional flow magnetic resonance imaging (4D-Flow MRI) and high-resolution MRI (HR-MRI). Initially, we curated a prospective dataset, dubbed the primary cohort, by aggregating patient data that was consecutively enrolled across two centers from November 2018 to November 2021. Unstable aneurysms were defined as those with symptoms, morphological change or ruptured during follow-up periods.

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Neuronal death plays a crucial role in early brain injury after subarachnoid hemorrhage (SAH). PANoptosis is a programmed form of cell death regulated by the PANoptosome, which possesses key characteristics of pyroptosis, apoptosis and necroptosis. Phosphoglycerate mutase family member 5 (PGAM5) has specific phosphatase activity that phosphorylates or dephosphorylates serine and threonine residues on bound proteins such as receptor-interacting protein kinase 1 (RIPK1), which are involved in programmed cell death.

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Background: Despite the widespread use in ischemic stroke, cancer, and malnutrition, the predictive ability of serum albumin to globulin ratio (A/G) among patients suffering from aneurysmal subarachnoid hemorrhage (aSAH) remains unknown. This study aimed to determine if serum A/G ratio is associated with the occurrence of delayed cerebral ischemia (DCI) after aSAH.

Methods: We retrospectively viewed the medical records of aSAH patients from 08/2017 to 08/2022.

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Objective: The aim of this study was to investigate the correlation between D-Dimer and unfavorable outcome after surgery for spontaneous supratentorial intracerebral hemorrhage(SSICH) METHODS: A total of 557 patients with spontaneous supratentorial intracerebral hemorrhage underwent surgical treatment, which included craniotomy evacuation of hematoma and puncture and drainage. Based on the modified Rankin Scale (mRS) bifurcation, the patients were divided into two subgroups: favorable outcome (mRS score 0-2) and unfavorable outcome (mRS score 3-5). D-dimer levels were measured within 24 h of admission, monitored until discharge, and grouped by quartiles (Q1-Q4).

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Background: Vertebral artery stenosis (VAS) and vertebral aneurysms are serious conditions that can be life-threatening and have a poor prognosis. The co-occurrence of VAS and a vertebral aneurysm is less common and more difficult to treat.

Observations: The authors report the case of a patient who presented with a rare occurrence of VAS combined with a vertebral aneurysm.

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Background: Glioblastoma multiforme (GBM) with synchronous metastasis(SM) is a rare occurrence. We extracted the data of GBM patients from the SEER database to look into the incidence of SM in GBM, determine the prognostic significance of SM in GBM, and assess therapeutic options for patients presenting with SM.

Methods: From 2004 to 2015, information on GBM patients was obtained from the Surveillance, Epidemiology, and End Results (SEER) database.

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Rationale: Wilson disease is an autosomal recessive genetic disease found by Samuel Alexander Kinnier Wilson and prevalent in childhood and adolescents.

Patient Concerns: An 18-year-old female patient presented to our hospital with a continuous decrease of 3 blood cell lines for more than 10 days, and diagnosed as decompensated cirrhosis. Ultrasonography showed diffuse lesions in the hepatic parenchyma, with multiple hypoechoic light masses in the parenchyma, the outline was still clear, and the internal echo was uneven.

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Background: The Fontan operation provides lifesaving palliation for individuals with single ventricle (SV) physiology. Given recent concerns of systemic disease (SD) for patients with a Fontan circulation, we sought to (1) quantify the increase in SD incidence associated with the Fontan circulation; (2) identify the risk factor of SD; (3) assess the association between SD and mortality in patients with a Fontan circulation.

Methods: A matched retrospective cohort study design was adopted.

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Article Synopsis
  • The study aimed to compare the effects of acarbose and metformin on thyroid function in patients with type 2 diabetes, especially focusing on thyroid stimulating hormone (TSH) levels.
  • A total of 788 patients were assigned to receive either acarbose or metformin for 48 weeks, with evaluations conducted at multiple intervals to measure changes in thyroid function and hormone sensitivity.
  • The results showed that both medications had similar effects on lowering TSH levels in patients with subclinical hypothyroidism but did not significantly change TSH levels in those with normal thyroid function.
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  • * This study introduces a synthetic metabolic pathway where hemicellulose-degrading enzymes are displayed on the surface of engineered E. coli bacteria, improving the breakdown of xylan, a key hemicellulose component.
  • * The research also showcases a microbial fuel cell (MFC) that uses these engineered bacteria, achieving a voltage of 0.71 V and producing α-ketoglutarate, demonstrating a new method to convert renewable biomass into valuable products and electricity sustainably.
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Tuberculosis (TB) is a global infectious threat, and the emergence of multidrug-resistant TB has become a major challenge in eradicating the disease that requires the discovery of new treatment strategies. This study aimed to elucidate the immune infiltration and molecular regulatory network of T cell-interacting activating receptors on myeloid cell 1 ()-related genes based on a bioinformatics analysis. The GSE114911 dataset was obtained from the Gene Expression Omnibus (GEO) and screened to identify 17 -related differentially expressed genes (TRDEGs).

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Observational studies indicate that variations in peripheral blood mononuclear cell (PBMC) subsets are associated with an increased risk of pulmonary tuberculosis (PTB) and coronavirus disease 2019 (COVID-19), but causal validation is lacking. Here, we combined single-cell expression quantitative trait locus (sc-eQTL) and two-sample mendelian randomization (MR) analyses to elucidate the causal relationship between PBMC subsets and the occurrence of PTB and COVID-19 and verified by RT-qPCR. We observed an increase in the CD4 Effective Memory T Cell (CD4 T) cluster in both PTB and COVID-19 patients according to the single-cell transcriptional landscape of PBMC.

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Lateral flow immunoassay (LFIA) is valued for its simplicity and rapidity for on-site screening, however, it experienced false negatives in real sample analysis due to low sensitivity. Although many signal amplification techniques can improve the sensitivity, they usually require additional complicated steps. To address these issues, taking () antibodies as a model detecting target, herein, we report an all-in-one LFIA (AIO-LFIA) with triple-step signal amplification to significantly improve sensitivity while maintaining simplicity.

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Background: Intermediate cells are present in the early stages of human prostate development and adenocarcinoma. While primary cells isolated from benign human prostate tissues or tumors exhibit an intermediate phenotype in vitro, they cannot form tumors in vivo unless genetically modified. It is unclear about the stem cell properties and tumorigenicity of intermediate cells.

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Background: Cardiovascular complications due to viral infection pose a significant risk in vulnerable patients such as those with congenital heart disease (CHD). Limited data exists regarding the incidence of influenza and its impact on cardiovascular outcomes among this specific patient population.

Methods: A retrospective cohort study was designed using the Canadian Congenital Heart Disease (CanCHD) database-a pan-Canadian database of CHD patients with up to 35 years of follow-up.

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Article Synopsis
  • Recent trials have found no advantage of endovascular stenting over aggressive medical management for patients with symptomatic intracranial atherosclerotic stenosis (sICAS), but balloon angioplasty has not yet been conclusively tested.
  • This study aimed to compare the effectiveness of balloon angioplasty plus aggressive medical management against aggressive medical management alone in sICAS patients.
  • Results showed that patients who received balloon angioplasty had a significantly lower incidence of strokes or death within the follow-up period compared to those receiving only medical management (4.4% versus 13.5%).
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Gallium (Ga) with a low melting point can serve as a unique metallic solvent in the synthesis of intermetallic compounds (IMCs). The negative formation enthalpy of transition metal-Ga IMCs endows them with high catalytic stability. Meanwhile, their tunable crystal structures offer the possibility to tailor the configurations of active sites to meet the requirements for specific catalytic applications.

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  • The study investigates the role of the systemic inflammatory response index (SIRI) in predicting the risk of stroke-associated pneumonia (SAP) in patients who have undergone thrombectomy for acute ischemic stroke (AIS).
  • Researchers analyzed 84 AIS patients treated with thrombectomy, finding that 66.7% developed SAP, with significant predictors identified including SIRI and age.
  • The results suggest that SIRI is a strong independent predictor for SAP, helping medical professionals identify high-risk AIS patients early based on their SIRI values.
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