Elucidating Cyathula Officinals' mechanism in osteoarthritis treatment: Network pharmacology and empirical evidence on anti-inflammatory actions.

In this study, we explored the therapeutic potential of Cyathula Officinals (CNX) in Knee Osteoarthritis (KOA) treatment. Utilizing network pharmacology and in vitro experiments, we identified active ingredients, action targets and pathways in CNX. Our analysis, integrating databases like TCMSP, SwissTarget Prediction, Genecards, CTD, STRING, and DAVID, highlighted 396 action targets and 283 disease targets, pinpointing 64 intersection genes linked to KOA.

NAC Transcription Factor Positively Regulates Drought Stress Responses in Arabidopsis and Triticale.

The NAC transcription factors play important roles in regulating plant growth, development, and senescence, and responding to biotic and abiotic stressors in plants. A novel coding sequence (1,059 bp) was cloned from hexaploid triticale in this study. The putative protein (352 amino acids) encoded by this sequence was over 95% similar to the amino acid sequence of a NAC protein from (XP020161331), and it formed a clade with , durum wheat, and barley.

New insights on structure of lignin-carbohydrate complex from hot water pretreatment liquor.

To understand the lignin-carbohydrate linkages and the structure changes in hot water pretreatment process, lignin-carbohydrate complex (LCC) fraction was extracted from hot water pretreatment liquor of poplar for the first time. Various structural analyses of LCC fraction were performed by different methods including high performance anion exchange chromatography, gel permeation chromatography, ultraviolet-visible spectroscopy, Fourier transform infrared spectroscopy and two-dimensional nuclear magnetic resonance spectroscopy. The results show that the lignin in LCC fraction mainly composed of syringyl unit, which was connected with β-O-4´ linkage.

Exploration of Highly Efficient Blue-Violet Light Conversion Agents for an Agricultural Film Based on Structure Optimization of Triphenylacrylonitrile.

To obtain highly efficient blue-violet light conversion agents used for an agricultural film, six triarylacrylonitrile derivatives and their doping films were prepared. Further, the luminogens have the ability to convert ultraviolet light into blue-violet light and exhibit aggregation-dependent fluorescence emission and high-contrast fluorescence quantum yields from 0.004 to 0.