Publications by authors named "Lital Oz Alcalay"
Article Synopsis
- ACKR1/DARC-associated neutropenia (ADAN) is a common benign blood condition, primarily affecting people of African and Jewish Yemenite descent, caused by a specific genetic variant.
- A study conducted in Israel from 2018-2023 assessed 115 children with isolated neutropenia, finding that 42.6% had ADAN, with a significant portion presenting severe neutropenia.
- The research suggests that ADAN doesn't increase infection risk and advocates for genetic testing in children with neutropenia to streamline diagnosis and potentially reduce unnecessary treatments.
Suppurative cervical lymphadenitis sometimes resolves with oral antibiotic treatment; however, many children are hospitalized for intravenous treatment due to lack of improvement. When there is no substantial improvement, the possibility of a liquefaction process is considered, and as a result, source control such as needle aspiration or open surgical drainage is recommended. We examined, among pediatric patients hospitalized with suppurative cervical lymphadenitis, clinical and laboratory predictors for invasive intervention that may lead to early imaging and intervention, hasten recovery, and shorten length of hospitalization.
View Article and Find Full Text PDFObjectives: The aim of this study was to assess the association between neonatal SARS-CoV-2 antibody level at delivery and infant SARS-CoV-2 infection under the age of 6 months and to identify predictive factors for neonatal antibody level at delivery.
Methods: In a prospective observational study, conducted between September 2021 and mid-February 2022, cord blood sera were tested for SARS-CoV-2 anti-spike receptor-binding domain antibodies after maternal BNT162b2 vaccination or infection. Infants were followed up for 6 months for SARS-CoV-2 infection.
Article Synopsis
- COVID-19 significantly impacts patients worldwide, with particular concern for pediatric patients undergoing cancer treatment, but data on their experiences during this period are limited.
- A study tracked 18 pediatric cancer patients diagnosed with COVID-19 while receiving antineoplastic therapy, revealing varied symptom severity—most experienced mild or no symptoms, and all eventually recovered.
- The findings suggest that continuing antineoplastic treatment is generally safe for asymptomatic or mildly symptomatic patients with COVID-19, with only a minority experiencing treatment delays.
Background: Respiratory syncytial virus (RSV)-related bronchiolitis is a common cause of morbidity in young infants. The recommendations for its passive prevention by palivizumab are currently under intensive debate.
Objectives: To elucidate the optimal prevention strategy by studying the morbidity of RSV disease under the current recommendations for palivizumab prophylaxis in Israel.