Twin pregnancies face a high risk of extreme preterm birth (PTB) under 28 weeks, linked to serious health issues for newborns, and current treatments are limited.
A potential solution is the placement of a vaginal cerclage for women with a short cervix or cervical dilatation, aiming to reduce the chances of extreme PTB.
Two multicenter trials are planned in the Netherlands to evaluate the effectiveness of vaginal cerclage compared to standard care in these women, with specific recruitment goals and an analysis of costs and outcomes.