Publications by authors named "Lisha Yang"

Breast cancer (BC) is the most frequently diagnosed and the leading cause of cancer-related deaths among women worldwide. It is crucial to develop a cost-effective BC genetic panel for detection and diagnosis. In this study, tissue samples from 52 BC patients and peripheral blood samples from 18 healthy volunteers were collected in western China, followed by gDNA extraction.

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Efficiently and economically recovering volatile fatty acids (VFAs) from sludge anaerobic fermentation (AF) poses a significant challenge. This study discovered a synergistic enhancement effect on VFAs production and membrane fouling control by combining polyethylene (PE) biocarriers and dynamic membrane technology (DM) in an anaerobic bioreactor. The reduced sludge particle size and enhanced hydrolysis efficiency led to a VFAs yield of 1200 mg/L, which is 2.

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Sludge pretreatment plays a crucial role in solubilizing particulate matters to release organic matter for subsequent anaerobic fermentation (AF). This study innovatively combines radio frequency (RF) heating and alkaline treatment, and finds that the combined pretreatment achieved a sludge disintegration rate of 35.11 %, which is 15.

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Background: The occurrence of non-alcoholic fatty liver disease (NAFLD) is increasing worldwide. The link between serum remnant cholesterol (RC) to high-density lipoprotein cholesterol (HDL-C) ratio and NAFLD remains unclear. Therefore, we sought to clarify the relationship between the RC/HDL-C ratio and the NAFLD.

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Effective dewatering is vital for both sludge treatment and resource recovery. This study focuses on converting post-anaerobic digested sludge into biochar to enhance sludge dewatering. The sludge-derived biochar is further modified with polyacrylamide (PAM-ADBC) and applied with sulfuric acid-modified montmorillonite (HMTS) for better performance.

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Lu doped HfZrO(HZO) ferroelectric films were prepared on Pt/TiN/SiO/Si substrate by chemical solution deposition method, and an interfacial engineering strategy for improving the ferroelectric property was explored by capping the Lu doped HZO films with a cerium oxide layer. Compared with the Lu doped HZO film without the CeOcoating layer, the Lu doped HZO film with the CeOcoating layer has a larger remanent polarization (2= 34.72C cm) and presents weaker wake-up behavior, which result from the higher orthogonal phase ratio and the lower oxygen vacancy of the CeOcoated Lu doped HZO film.

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Isolated bovine adrenal chromaffin cells exposed to single 2-, 4-, or 5-ns pulses undergo a rapid, transient rise in intracellular Ca mediated by Ca entry via voltage-gated Ca channels (VGCCs), mimicking the activation of these cells in vivo by acetylcholine. However, pulse durations 150 ns or longer elicit larger amplitude and longer-lived Ca responses due to Ca influx via both VGCCs and a yet to be identified plasma membrane pathway(s). To further our understanding of the differential effects of ultrashort versus longer pulse durations on Ca influx, chromaffin cells were loaded with calcium green-1 and exposed to single 3-, 5-, 11-, 25-, or 50-ns pulses applied at their respective Ca activation threshold electric fields.

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The complexity and high cost to separate and recover short chain fatty acids (SCFAs), ammonium ions, and phosphates in the sludge fermentation liquid hinder the application of sludge anaerobic fermentation. In this study, an interesting phenomenon was found in a sludge anaerobic fermenter with a dynamic membrane (DM) which could not only enhance SCFAs production but also retain most SCFAs in fermenter. The separation factor of DM for NH-N/SCFAs and PO/SCFAs throughout the DM development were about 40 and 80, respectively.

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Anaerobic fermentation is an effective method to harvest volatile fatty acids (VFAs) from waste activated sludge (WAS). Accurately predicting and optimizing VFAs production is crucial for anaerobic fermentation engineering. In this study, we developed machine learning models using two innovative strategies to precisely predict the daily yield of VFAs in a laboratory anaerobic fermenter.

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The Tibetan people are ancient and populous, constituting the seventh-largest of the fifty-five ethnic minority groups in China. The Ngawa Tibetan and Qiang Autonomous Prefecture (NTQAP), situated on the border of northwest and southwest China, has its distinct group relationships. Short tandem repeat (STR) is extremely polymorphic and extensively used in the application of forensic medicine and population genetics.

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The aim of this study is to investigate the core competencies of midwives in China. Combination of qualitative research and quantitative research. A total of 100 midwives in 3 tertiary (Grade 3) hospitals in Shijiazhuang were investigated by using the Midwife Core Competency Scale, and simultaneously followed by semi-structured interviews with 12 midwives.

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Nonsyndromic hearing loss (NSHL) is a genetically diverse, highly heterogeneous condition characterised by deafness, and Gasdermin E (GSDME) variants have been identified as directly inducing autosomal dominant NSHL. While many NSHL cases associated with GSDME involve the skipping of exon 8, there is another, less understood pathogenic insertion variant specifically found in Chinese pedigrees that causes deafness, known as autosomal dominant 5 (DFNA5) hearing loss. In this study, we recruited a large Chinese pedigree, conducted whole-exome and Sanger sequencing to serve as a comprehensive clinical examination, and extracted genomic DNA samples for co-segregation analysis of the members.

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Despite its great potential to recover energy from waste sludge, anaerobic digestion (AD) still needs to solve issues such as slow hydrolysis and H inhibition. This study investigated the effects of coupling microbial electrolysis cell (MEC) with AD on the CH yield. Results and analysis show that the CH yield was significantly improved in MEC-AD reactors by two factors, i.

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Background And Aims: A functional cure, or hepatitis B virus (HBV) surface antigen (HBsAg) loss, is difficult to achieve in patients with hepatitis B virus e antigen (HBeAg)-positive chronic hepatitis B. The HBV vaccine and granulocyte-macrophage colony-stimulating factor (GM-CSF) have been reported to help reduce HBsAg levels and promote HBsAg loss. In this prospective randomized trial, we evaluated HBsAg loss in patients receiving pegylated interferon-α2b (PEGIFN-α2b) and tenofovir disoproxil fumarate (TDF), with and without GM-CSF and HBV vaccination.

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The Han nationality is an ancient and populous people, and different places in China may have their distinct group relationships. Luzhou area, as a crossroads of several provinces in Southwest China, lacks autosomal short tandem repeat (STR) research and population genetics research. In this study, 21 autosomal STR loci were evaluated in 1959 Han-Chinese individuals from Luzhou area.

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Article Synopsis
  • - The study discusses the development of a novel sandwich membrane (SESP) using epigallocatechin gallate (EGCG) and titanium nanoparticles (Ti NPs) for effective water purification, specifically targeting heavy metals like Cr(VI) and Cr(III).
  • - The SESP membrane demonstrated excellent stability and performance, achieving a high rate of water flux and efficient removal rates of heavy metals, with over 83% removal for simulated wastewater and 100% for actual wastewater after multiple use cycles.
  • - Mechanisms for heavy metal removal were identified, including the Donnan effect and electrostatic attraction, which facilitated the simultaneous removal of Cr(VI) and Cr(III), showcasing the membrane’s potential for environmental sustainability.
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Article Synopsis
  • * Using single-cell RNA sequencing, researchers identified specific immune cell types in CHB patients that change before and after IFN-α therapy, highlighting the therapy's role in regulating inflammation and enhancing the immune response.
  • * Overall, the study sheds light on the immune system effects of PegIFN-α in CHB, which could improve future diagnosis and treatment strategies for this chronic disease.
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Neurofibromatosis type 1 (NF1) presents an autosomal dominant, haploinsufficient, and multisystemic disorder with patches of skin café-au-lait spots, lisch nodules in the iris, even tumors in the peripheral nervous system or fibromatous skin. In this study, a Chinese young woman who suffered from NF1 disease with first-trimester spontaneous abortion was recruited. Analysis for whole exome sequencing (WES), Sanger sequencing, short tandem repeat (STR), and co-segregation was carried out.

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Purpose: Acupuncture has been widely used in the treatment of knee osteoarthritis (KOA), but the selection of acupoints is indeterminate and lacks biological basis. The skin temperature of acupoints can reflect the state of local tissue and may be a potential factor for guiding acupoint selection. This study aims to compare the skin temperature of acupoints between KOA patients and the healthy population.

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SRY-box transcription factor 9 (SOX9) (OMIM 608160) is a transcription factor. The expression of SOX9 in pan-cancers and the regulation by small molecules in cancer cell lines are unclear. In the current study, we comprehensively analyzed the expression of SOX9 in normal tissues, tumor tissues and their matched healthy tissues in pan-cancers.

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The countries along the "Belt and Road" (B&R) have close cooperative connections economically and in trade, and these connections lead to a large amount of embodied carbon emissions and have formed a complex network of net carbon transfers. Considering 63 countries and 26 sectors, this study uses the Eora multiregional input-output (MRIO) model to construct the embodied carbon transfer networks in 1992, 1998, 2004, 2010, and 2016. Additionally, it applies the social network approach to analyze the structural characteristics and evolution of carbon flow networks in the countries and regions along the B&R.

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Numerous studies have explored the adsorption of cadmium (Cd) and arsenic (As) by iron (Fe)-modified biochar, but few studies have examined in-depth the similarities and differences in the adsorption behavior of different iron types on Cd and As. In this study, sewage sludge biochar (BC) was co-pyrolyzed with self-made Fe minerals (magnetite, hematite, ferrihydrite, goethite, and schwertmannite) to treat Cd and As co-contaminated water. The adsorption of Cd and As on the Fe-modified biochar was further analyzed by adsorption kinetics, adsorption isotherms, and adsorption thermodynamics combined with a series of characterization experiments.

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Background: Neurofibromatosis type 1 (NF1) is an autosomal dominant with haploinsufficient, and multisystemic disorder including patches of skin Café-au-lait spots, Lisch nodules in the iris, and tumors in the peripheral nervous systems or fibromatous skin.

Methods: Blood samples were collected and DNA was extracted from a large Chinese pedigree suffering from NF1 disease with three spontaneous abortions or death for proband. Analysis for whole exome sequencing (WES), Sanger sequencing, and co-segregation was carried out.

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Rice is the main food in China, and its pollution by heavy metals has attracted widespread attention. In this study, rice grain samples were collected from 14 prefecture-level cities in Hunan Province, China. The contents of 9 heavy metals (i.

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Knowledge of the fate and transport of metal-organic frameworks (MOFs) in porous media is essential to understanding their environmental impacts. However, to date, the transport mechanisms of MOFs are not fully revealed. Meanwhile, surfactants can promote MOFs dispersion by forming a stable suspension.

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