Publications by authors named "Lisha Su"
Background: China's language therapist shortage and intergenerational caregiving trends underscore the need for family-based language training, yet such interventions are underutilized and family roles undervalued. This study aims to investigate the effect of a therapist-led family-centered intervention on children with language delay.
Methods: The study comprised 134 children, comprising 59 girls and 75 boys, aged between 2 and 5 years (39.
Objective: This study aimed to investigate the clinical effects of Orff music therapy on children with Autism Spectrum Disorder (ASD) from the perspectives of parents, evaluators, and therapists.
Methods: 93 children with ASD aged 3-6 years participated in the study. They were divided into an observation group ( = 48) receiving comprehensive rehabilitation intervention including Orff music therapy, and a control group ( = 45) receiving only comprehensive rehabilitation intervention.
[Prenatal diagnosis of a case with Schuurs-Hoeijmakers syndrome].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
November 2023
Objective: To explore the genetic basis for a fetus with multiple malformations.
Methods: Clinical data of the fetus was collected, Amniotic fluid sample of the fetus was subjected to conventional G-banded karyotyping, low-depth whole genome copy number variants detection and whole exome sequencing (WES). Candidate variant was verified by Sanger sequencing of the fetus and its parents.
[Clinical features and genetic analysis of a child with glycogen storage disease type VI].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
October 2022
Article Synopsis
- - The study aims to investigate a 3-year-old boy with glycogen storage disease VI (GSD-VI) to understand his clinical symptoms and genetic causes.
- - Clinical assessments showed he had symptoms like abdominal distention, hepatomegaly, and elevated liver enzymes, while whole exome sequencing identified two genetic variants in the PYGL gene inherited from each parent.
- - The findings highlight the significance of these mutations in causing GSD-VI and expand knowledge on PYGL gene variants, aiding in potential treatments and genetic counseling for affected families.
Article Synopsis
- The study aimed to assess the impact of functional chewing training (FuCT) on chewing ability, tongue thrust severity, and drooling in children with cerebral palsy.
- A total of 48 children with oral motor dysfunction were randomly assigned to either FuCT or oral motor training groups for 12 weeks, with evaluations performed post-training.
- Results showed that the FuCT group experienced significant improvements in masticatory function, tongue thrust severity, and drooling compared to the oral motor training group, proving FuCT to be beneficial for these outcomes.
[Analysis of a family with recurrent fetal copy number variations in 1p31.1].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
November 2019
Objective: To analyze a family with recurrent fetal copy number variations (microdeletion and microduplication, respectively) of 1p31.1 using single nucleotide polymorphism-based array (SNP-array) and G banding chromosomal karyotyping.
Methods: Amniocentesis and chorionic villus sampling were performed for a woman during the two pregnancies.
TPX2 siRNA regulates growth and invasion of esophageal cancer cells.
Biomed Pharmacother
September 2014
Purpose: Observe how specific small RNA interference (siRNA) aimed at TPX2 gene suppresses TPX2 gene expression in esophageal cancer EC9706 cells and the effect on esophageal cancer cell growth and invasion ability.
Methods: Transfect TPX2 siRNA into EC9706 cells via lipofectamin 2000. The experiments were divided into three groups, a negative control, a blank control and an siRNA interference group (24h, 48h, 72h, 96h).
[Adenoid cystic carcinoma of ENT associated with hard lump: a report of 9 cases].
Lin Chuang Er Bi Yan Hou Ke Za Zhi
October 2006
Objective: To assess the clinical and pathological features of the patients with ENT adenoid cystic carcinoma (ENTACC) who presented with hard lump, and to detect its prognosis.
Method: A retrospective analysis was performed on 9 patients with ENTACC by their clinical data.
Result: The period from the occurrence of primary symptoms to definite diagnosis was 4 years and 3 months on average.