[Influence of the viral subtype in the progression of HIV patients].

A longitudinal study of 161 HIV-positive patients seen at "Pedro Kouri" Institute of Tropical Medicine was conducted to assess the influence of viral recombination in the outcome of patients infected by the human immunodeficiency virus type 1 (HIV-1). The cohort was divided into two groups: Recombinant and Non Recombinant, depending on the viral subtype or recombinant form accounting for the infection. The participants from each group were observed for 18 months and compared in terms of time to developing AIDS, frequency of opportunistic diseases, survival and speed of reduction of CD4 T lymphocytes.