Publications by authors named "Lise F E Beumeler"

Article Synopsis
  • Post-intensive care syndrome (PICS) can lead to long-term physical, psychological, and cognitive challenges for ICU survivors, and there's interest in how mitochondrial dysfunction may play a role in this condition.
  • A study analyzed 43 ICU survivors to look for connections between mitochondrial health (through mtDNA markers) and long-term physical functioning, but found no significant correlations between these factors.
  • The research highlights that PICS is influenced by many factors beyond just mitochondrial health, indicating a need for further studies to improve recovery strategies for ICU survivors.
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  • The paper develops a Context-specific Positive Health (CPH) measurement instrument, addressing the lack of tools that incorporate contextual factors impacting individuals' health.
  • This instrument was created and validated through focus groups and a survey of 1002 diverse Dutch participants, ensuring its reliability and validity.
  • The finalized CPH questionnaire evaluates 11 dimensions related to positive health, including resilience and social support, emphasizing the importance of adaptability in health outcomes.
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Article Synopsis
  • Many ICU survivors experience long-term health issues that can hinder their recovery and quality of life, with nutrition intake playing a critical role.
  • A study of 81 ICU patients found that a significant number failed to meet recommended protein and energy intake levels after 12 months, despite improvements from dietary supplements.
  • Improved nutrition care is necessary to help these patients achieve dietary adequacy, though simply increasing intake may not lead to better physical health outcomes.
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  • ICU survivors frequently experience long-term mental health issues, including symptoms of depression, anxiety, and PTSD, negatively impacting their recovery and quality of life.
  • The study surveyed 239 ICU patients over 12 months and found a 38% prevalence of mental frailty, identified using established clinical assessment tools.
  • The results stress the importance of creating comprehensive aftercare programs to support both survivors and their informal caregivers to improve mental health outcomes.
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Sepsis is a global health challenge, with over 49 million cases annually. Recent medical advancements have increased in-hospital survival rates to approximately 80%, but the escalating incidence of sepsis, owing to an ageing population, rise in chronic diseases, and antibiotic resistance, have also increased the number of sepsis survivors. Subsequently, there is a growing prevalence of "post-sepsis syndrome" (PSS).

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Background: Intensive care unit (ICU) survivors deal with long-term health problems, which negatively affect their quality of life (QoL). Nutritional and exercise intervention could prevent the decline of muscle mass and physical functioning which occurs during critical illness. Despite the growing amount of research, robust evidence is lacking.

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Article Synopsis
  • The study aims to assess changes in Health-Related Quality of Life (HRQoL) in ICU patients during the first year after their admission, focusing on the concerning rate of non-recovery (44%) observed in previous research.
  • It included 81 long-stay adult ICU patients, measuring HRQoL using the RAND-36 survey at various intervals post-admission, and found that 55% of patients did not fully recover, often needing more healthcare support.
  • The findings indicate that lower baseline HRQoL is linked to poorer long-term outcomes, highlighting the need for targeted care for patients at risk of long-term non-recovery.
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  • A study explored long-term physical recovery in patients who had extended stays in the ICU, revealing a significant number of individuals did not achieve full recovery by 12 months post-ICU.
  • Of the 250 patients analyzed, 44% were classified as non-recovery based on their physical functioning scores, with factors like age, gender, and pre-existing health issues influencing these outcomes.
  • Findings indicated that traditional ICU characteristics, such as illness severity, were not effective predictors of long-term recovery, highlighting the need for better assessment methods focusing on patients' physical functioning and comorbidities.
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