Publications by authors named "Lise C Gaudernack"
Background: Prolonged labor is a common condition associated with maternal and perinatal complications. The standard treatment with oxytocin for augmentation of labor increases the risk of adverse outcomes. Hyoscine butylbromide is a spasmolytic drug with few side effects shown to shorten labor when used in a general population of laboring women.
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- First-time mothers often experience prolonged labor, which can affect about 20% of them and lead to negative birth outcomes; oxytocin is commonly used but has drawbacks.
- This study aims to determine if the antispasmodic drug butylscopolamine bromide (Buscopan®) can effectively shorten labor duration for first-time mothers who show signs of slow progress, as assessed by the World Health Organization partograph.
- Conducted at Oslo University Hospital, the trial will involve 250 women, comparing the effects of butylscopolamine to a placebo on labor duration, pain levels, need for oxytocin, delivery method, and overall maternal experience.
Background: Since Misoprostol Vaginal Insert (MVI - Misodel ®) was approved for labor induction in Europe in 2013, to date, no study has been published comparing MVI to Misoprostol vaginal tablets (MVT). The aim of this study, performed as part of a quality improvement project, was to compare the efficacy and safety of 200 μg MVI versus 25 μg MVT for labor induction in nulliparous women.
Methods: This retrospective cohort study included 171 nulliparous singleton term deliveries induced with MVI (n = 85) versus MVT (n = 86) at Oslo University Hospital Rikshospitalet, Norway, from November 2014 to December 2015.
Background: The objective was to investigate whether acupuncture could be a reasonable option for augmentation in labor after spontaneous rupture of membranes at term and to look for possible effects on the progress of labor.
Methods: In a randomized controlled trial 100 healthy parturients, with spontaneous rupture of membranes at term, were assigned to receive either acupuncture or no acupuncture. The main response variables were the duration of active labor, the amount of oxytocin given, and number of inductions.