Building a responsible innovation toolkit as project legacy.

This article explores whether and in what way it is possible to employ toolkits for responsible research and innovation (RRI toolkits) as mechanisms for ensuring the legacy of RRI in research projects. Based on a review of the concept of responsible research and innovation as well as existing toolkits in the area, the article offers an account of the development of an RRI toolkit in the context of the EU- funded Human Brain Project. This toolkit is designed to integrate insights and practices of responsible research and innovation developed over a 10 year period into the project legacy, the EBRAINS research infrastructure.

Linking Brain Structure, Activity, and Cognitive Function through Computation.

Understanding the human brain is a "Grand Challenge" for 21st century research. Computational approaches enable large and complex datasets to be addressed efficiently, supported by artificial neural networks, modeling and simulation. Dynamic generative multiscale models, which enable the investigation of causation across scales and are guided by principles and theories of brain function, are instrumental for linking brain structure and function.

The innovation journey of genomics and asthma research.

This article concerns the transformative potential of medical genomics for common disease research. We analysed 13 review articles in asthma research in the period 1999 to 2008. Our aim was to understand how genomics has emerged in this research field, and the attendant changes.