Publications by authors named "Lise B Toustrup"
Background: infections resurged globally in 2023-2024 after a three-year decline during the COVID-19 pandemic. We explored the incidence and severity of infections in children and adolescents before, during, and after the pandemic.
Methods: This nationwide, population-based cohort study included all Danish children and adolescents aged 0-17 years with a positive PCR test from May 1, 2016, to April 30, 2024.
Article Synopsis
- The study evaluates kidney function and abnormalities in children with congenital solitary functioning kidney (SFK) due to multicystic dysplastic kidney (MCDK) or unilateral renal agenesis (URA).
- A review of medical records from 154 children revealed that 8% had abnormalities in their SFK, with hydronephrosis being the most common, and 46% of those abnormalities resolved spontaneously.
- The majority of the children maintained normal kidney function, with a standard GFR above 75%, but those with SFK abnormalities presented a higher risk of reduced GFR.
Background/aim: Variability in the severity and age at onset of autosomal dominant familial neurohypophyseal diabetes insipidus (adFNDI) may be associated with certain types of variants in the arginine vasopressin (AVP) gene. In this study, we aimed to describe a large family with an apparent predominant female occurrence of polyuria and polydipsia and to determine the underlying cause.
Methods: The family members reported their family demography and symptoms.
Autosomal dominant familial neurohypophyseal diabetes insipidus (adFNDI) is caused by variants in the arginine vasopressin (AVP) gene. Here we report the generation of induced pluripotent stem cells (iPSCs) from a 42-year-old man carrying an adFNDI causing variant in exon 1 of the AVP gene using lentivirus-mediated nuclear reprogramming. The iPSCs carried the expected variant in the AVP gene.
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