A double-blind controlled study of a nonhydroquinone bleaching cream in the treatment of melasma.

Background: Melasma is an acquired hypermelanosis predominantly affecting the face of women. It is often recalcitrant to treatment with hypopigmenting agents.

Objective: To assess the efficacy of a nonhydroquinone cream (Amelan M) vs.

Non-ablative skin remodeling: an 8-month clinical and 3D in vivo profilometric study with an 810 nm diode laser.

Background: Non-ablative remodeling has recently been proposed as a new anti-aging treatment with no downtime.

Objective: This study aimed to evaluate objectively, with a three-dimensional (3D) in vivo profilometric study, the efficacy and safety of non-ablative skin remodeling with an 810 nm diode laser on periorbital wrinkles with an 8-month follow-up.

Methods: Ten female patients (mean age: 55 years) were treated three times at 1-month intervals and then evaluated 5 months after the last treatment.