Imprinting and locking chiral memory for stereoselective catalysis.

A salen ligand based Co(III) complex +/- with imprintable chiral memory was locked-in and used for stereoselective catalysis.

Preorganization in highly enantioselective diaza-Cope rearrangement reaction.

Crystal structure and activation entropy data indicate that H-bond directed diaza-Cope rearrangement of chiral diimines takes place with a high degree of preorganization. CD spectroscopy and HPLC data show that there is inversion of stereochemistry for the reaction with excellent enantioselectivity.