Publications by authors named "Lisa Shigematsu"
Social impact of brain fog and analysis of risk factors: Long COVID in Japanese population.
Ann Clin Transl Neurol
August 2024
Article Synopsis
- This study investigates brain fog in COVID-19 patients, focusing on its clinical features and societal impact, particularly on work productivity.
- A cohort of 1,009 hospitalized patients was analyzed, revealing that brain fog symptoms decreased after 3 months but remained stable up to 12 months, with certain neurological symptoms correlating to higher brain fog instances.
- Key risk factors were identified, including advanced age, female sex, obesity, and pre-existing respiratory issues, with findings indicating that brain fog negatively affects labor productivity.
Background: Companion diagnostic tests play a crucial role in guiding treatment decisions for patients with non-small cell lung cancer (NSCLC). The Oncomine Dx Target Test (ODxTT) Multi-CDx System has emerged as a prominent companion diagnostic method. However, its efficacy in detecting driver gene mutations, particularly rare mutations, warrants investigation.
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- * Data from 1200 enrolled patients showed a decline in symptoms over time, from 93.9% during hospitalization to 33.0% at 12 months, with those experience long COVID symptoms reporting lower quality of life and higher anxiety and depression.
- * Identified risk factors for long COVID included being female, middle-aged, requiring oxygen, and being in critical condition during hospitalization, providing valuable insights for future research in Japan.
We report the first case of a patient with non-small cell lung cancer (NSCLC) with malignant pleural effusion (MPE) who achieved disease- and treatment-free survival for nearly 10 years. A 50-year-old man was diagnosed with NSCLC with MPE and underwent chemotherapy and salvage thoracic surgery. The patient received chemotherapy with cisplatin, pemetrexed, and bevacizumab, and a partial response was achieved.
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