Publications by authors named "Lisa Quadri"
Pediatr Nephrol
November 2024
Article Synopsis
- A significant portion of atypical hemolytic uremic syndrome (aHUS) in children is linked to autoantibodies against complement factor H, prompting treatments like plasma exchange and eculizumab.
- In a study of 12 children treated with eculizumab, varying immunosuppressive strategies were used, but the decrease in anti-FH antibody levels was consistent regardless of the regimen.
- The study concluded that eculizumab is a safe and effective long-term treatment for aHUS related to anti-FH antibodies, and combining it with mycophenolate mofetil (MMF) may be sufficient for management.
