Backscatter from therapeutic doses of ionizing irradiation does not impair cell migration on titanium implants in vitro.

Objective: The influence of radiation backscatter from titanium on DNA damage and migration capacity of human osteoblasts (OBs) and mesenchymal stem cells (MSCs) may be critical for the osseointegration of dental implants placed prior to radiotherapy. In order to evaluate effects of radiation backscatter, the immediate DNA damage and migration capacity of OBs and MSCs cultured on titanium or plastic were compared after exposure to ionizing irradiation.

Materials And Methods: Human OBs and MSCs were seeded on machined titanium, moderately rough fluoride-modified titanium, or tissue culture polystyrene, and irradiated with nominal doses of 2, 6, 10, or 14 Gy.

The dose-dependent impact of γ-radiation reinforced with backscatter from titanium on primary human osteoblasts.

In head and neck cancer patients receiving dental implants prior to radiotherapy, backscatter from titanium increases the radiation dose close to the surface, and may affect the osseointegration. The dose-dependent effects of ionizing radiation on human osteoblasts (hOBs) were investigated. The hOBs were seeded on machined titanium, moderately rough fluoride-modified titanium, and tissue culture polystyrene, and cultured in growth- or osteoblastic differentiation medium (DM).

Effects of ionizing irradiation and interface backscatter on human mesenchymal stem cells cultured on titanium surfaces.

Radiotherapy to the head and neck region negatively influences the osseointegration and survival of dental implants. The effects of cobalt 60 ( Co) ionizing radiation and the impact of backscatter rays were investigated on human mesenchymal stem cells cultured on titanium surfaces. Bone marrow-derived human mesenchymal stem cells were seeded on titanium (Ti), fluoride-modified titanium (TiF), and tissue culture plastic.

Clinical performance of enamel-dentine bonded all-ceramic restorations: retrospective evaluation in a postgraduate clinic.

The aim of this retrospective study was to evaluate the clinical survival and success of five dif- ferent types of adhesive bonded all-ceramic restorations, in a postgraduate clinic. All ceramic enamel-dentin adhesive bonded restorations, either partial (n=94) or full coverage (n=145), were assessed by clinical examination using a modified Californian Dental Association (CDA) system for quality evaluation of dental care and a questionnaire assessing patient satis- faction (VAS) of 29 subjects with 239 restorations. The same 3-step adhesive bonding system in combination with dual-cured resin composite cement was used for all restorations Rubber dam was used for moisture control.