BLOOD AND TISSUE ENZYME ACTIVITIES IN BEARDED DRAGONS ().

Bearded dragons () are a common reptile species kept under human care and suffer from a wide range of diseases for which plasma biochemistry is used as a first-line diagnostic test. There is limited information available regarding tissue enzyme activities and origin that could assist in interpreting the bearded dragon plasma biochemistry enzymology profile. The aim of this study was to characterize the tissue activities of seven enzymes routinely used in the reptile biochemistry panel: alkaline phosphatase (ALP), alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma-glutamyl transferase (GGT), glutamate dehydrogenase (GLDH), lactate dehydrogenase (LDH), and creatine kinase (CK) in 12 adult inland bearded dragons in 13 tissues, plasma, and red blood cells.

Hepatic lipid accumulation is associated with multiple metabolic pathway alterations but not dyslipidemia and insulin resistance in central bearded dragons (Pogona vitticeps).

Objective: To investigate associations between hepatic fat accumulation, fibrosis, and plasma values of primary metabolites, biochemical measurands, insulin, and lipoproteins in bearded dragons.

Animals: 48 adult central bearded dragons (Pogona vitticeps).

Methods: Dragons were sedated with alfaxalone, and a blood sample was collected.

Expression of IL-20 Receptor Subunit β Is Linked to EAE Neuropathology and CNS Neuroinflammation.

Considerable clinical evidence supports that increased blood-brain barrier (BBB) permeability is linked to immune extravasation of CNS parenchyma during neuroinflammation. Although BBB permeability and immune extravasation are known to be provoked by vascular endothelial growth factor-A (i.e.